Hepatic stem cells and the liver’s maturational lineages: Implications for liver biology, gene expression, and cell therapies

Eva Schmelzer, Randall E. McClelland, Aloa Melhem, Lili Zhang, Hsin Lei Yao, Eliane Wauthier, William S. Turner, Mark E. Furth, David Gerber, Sanjeev Gupta, Lola M. Reid

Research output: Chapter in Book/Report/Conference proceedingChapter

17 Scopus citations

Abstract

Numerous excellent articles and reviews have been published within the last several years on developmental biology of the liver (1,2), on hepatic precursors found in bone marrow (3–6), and on oval cells and oval cell lines (7–10). In this review, we have focused on studies on normal hepatic stem-cell and liver lineage biology not covered by these prior reviews. The readers should refer to the prior reviews for summaries of the literature ignored here. Table 1 provides definitions of terms used throughout the review.

Original languageEnglish (US)
Title of host publicationTissue Stem Cells
PublisherCRC Press
Pages161-214
Number of pages54
ISBN (Electronic)9781420016833
ISBN (Print)9780824728991
StatePublished - Jan 1 2006

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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    Schmelzer, E., McClelland, R. E., Melhem, A., Zhang, L., Yao, H. L., Wauthier, E., Turner, W. S., Furth, M. E., Gerber, D., Gupta, S., & Reid, L. M. (2006). Hepatic stem cells and the liver’s maturational lineages: Implications for liver biology, gene expression, and cell therapies. In Tissue Stem Cells (pp. 161-214). CRC Press.