TY - JOUR
T1 - Henoch Schonlein Purpura as a Cause of Renal Failure in an Adult
AU - Kukrety, Shweta
AU - Vimalachandran, Pradeepa
AU - Kunadharaju, Rajesh
AU - Mehta, Vishisht
AU - Colanta, Agnes
AU - Abu Hazeem, Mahmoud
N1 - Publisher Copyright:
© 2016 Shweta Kukrety et al.
PY - 2016
Y1 - 2016
N2 - Henoch Schonlein purpura (HSP) is an immune mediated disease associated Immunoglobulin A (IgA) deposition within the affected organs. While the disease is commonly seen in the pediatric age group, it is rarely seen in adults. We report the case of a 93-year-old Caucasian lady who presented with nonthrombocytopenic purpuric rash and acute kidney injury after an episode of bronchitis. Rapid and progressive deterioration of renal function prompted a kidney biopsy, which showed findings consistent with IgA nephropathy confirming the diagnosis of HSP. The patient was treated with high dose intravenous methylprednisolone followed by oral prednisone; however, her kidney disease progressed to end stage renal disease requiring hemodialysis. HSP is usually a self-limiting disease in children. However, adults are at an increased risk of severe renal involvement including end stage renal disease. Purpuric skin rash with renal involvement should raise suspicion for HSP. This is the oldest known patient with HSP.
AB - Henoch Schonlein purpura (HSP) is an immune mediated disease associated Immunoglobulin A (IgA) deposition within the affected organs. While the disease is commonly seen in the pediatric age group, it is rarely seen in adults. We report the case of a 93-year-old Caucasian lady who presented with nonthrombocytopenic purpuric rash and acute kidney injury after an episode of bronchitis. Rapid and progressive deterioration of renal function prompted a kidney biopsy, which showed findings consistent with IgA nephropathy confirming the diagnosis of HSP. The patient was treated with high dose intravenous methylprednisolone followed by oral prednisone; however, her kidney disease progressed to end stage renal disease requiring hemodialysis. HSP is usually a self-limiting disease in children. However, adults are at an increased risk of severe renal involvement including end stage renal disease. Purpuric skin rash with renal involvement should raise suspicion for HSP. This is the oldest known patient with HSP.
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U2 - 10.1155/2016/7890379
DO - 10.1155/2016/7890379
M3 - Article
AN - SCOPUS:85032641806
SN - 1687-9627
VL - 2016
JO - Case Reports in Medicine
JF - Case Reports in Medicine
M1 - 7890379
ER -