Abstract
Article abstract-Motivationally responsive motor deficits may occur in isolation or as part of more general neglect syndromes. We describe three patients with two discrete syndromes of isolated motor neglect, differentiated primarily by their performance in motor tasks enacted within or toward the contralesional hemispace. The lesions in our patients likely disrupted attentional interactions with two separable sensorimotor processing subsystems. Physiologic data support the existence of a parietal-lateral premotor circuit that processes information encoded in spatial coordinates referenced to the extrapersonal environment and of a basal ganglionic-mesial premotor circuit that processes information mostly encoded in egocentric skeletomotor coordinates. The correlation of ischemic lesions resulting in hemispatial and directional biases in motor neglect with disruption of known physiologic subsystems may provide the basis for rational cognitive rehabilitation of these higher-order motor deficits. These observations are supported by recent PET studies that document the presence of specific attentional-motoric interactions within discrete processing components of a distributed sensorimotor attentional network.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 525-531 |
| Number of pages | 7 |
| Journal | Neurology |
| Volume | 45 |
| Issue number | 3 |
| State | Published - 1995 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Clinical Neurology
Cite this
Hemispatial and directional performance biases in motor neglect. / Simon, Ely S.; Hegarty, Angela M.; Mehler, Mark F.
In: Neurology, Vol. 45, No. 3, 1995, p. 525-531.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hemispatial and directional performance biases in motor neglect
AU - Simon, Ely S.
AU - Hegarty, Angela M.
AU - Mehler, Mark F.
PY - 1995
Y1 - 1995
N2 - Article abstract-Motivationally responsive motor deficits may occur in isolation or as part of more general neglect syndromes. We describe three patients with two discrete syndromes of isolated motor neglect, differentiated primarily by their performance in motor tasks enacted within or toward the contralesional hemispace. The lesions in our patients likely disrupted attentional interactions with two separable sensorimotor processing subsystems. Physiologic data support the existence of a parietal-lateral premotor circuit that processes information encoded in spatial coordinates referenced to the extrapersonal environment and of a basal ganglionic-mesial premotor circuit that processes information mostly encoded in egocentric skeletomotor coordinates. The correlation of ischemic lesions resulting in hemispatial and directional biases in motor neglect with disruption of known physiologic subsystems may provide the basis for rational cognitive rehabilitation of these higher-order motor deficits. These observations are supported by recent PET studies that document the presence of specific attentional-motoric interactions within discrete processing components of a distributed sensorimotor attentional network.
AB - Article abstract-Motivationally responsive motor deficits may occur in isolation or as part of more general neglect syndromes. We describe three patients with two discrete syndromes of isolated motor neglect, differentiated primarily by their performance in motor tasks enacted within or toward the contralesional hemispace. The lesions in our patients likely disrupted attentional interactions with two separable sensorimotor processing subsystems. Physiologic data support the existence of a parietal-lateral premotor circuit that processes information encoded in spatial coordinates referenced to the extrapersonal environment and of a basal ganglionic-mesial premotor circuit that processes information mostly encoded in egocentric skeletomotor coordinates. The correlation of ischemic lesions resulting in hemispatial and directional biases in motor neglect with disruption of known physiologic subsystems may provide the basis for rational cognitive rehabilitation of these higher-order motor deficits. These observations are supported by recent PET studies that document the presence of specific attentional-motoric interactions within discrete processing components of a distributed sensorimotor attentional network.
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UR - http://www.scopus.com/inward/citedby.url?scp=0029010665&partnerID=8YFLogxK
M3 - Article
C2 - 7898710
AN - SCOPUS:0029010665
VL - 45
SP - 525
EP - 531
JO - Neurology
JF - Neurology
SN - 0028-3878
IS - 3
ER -