Hematolymphopoietic and inflammatory cytokines in neural development

Mark F. Mehler, John A. Kessler

Research output: Contribution to journalReview articlepeer-review

140 Scopus citations


It is now clear that cytokines traditionally viewed as immune modulators participate in inflammatory responses within the adult nervous system. However, in the developing nervous system hematolymphopoietic cytokines also play a role unrelated to neural-immune interactions. Instead, many of these factors subserve primary regulatory functions related both to the morphogenesis and to the cellular maturation of the central and peripheral nervous systems. This article focuses specifically on cytokine actions in neural development.

Original languageEnglish (US)
Pages (from-to)357-365
Number of pages9
JournalTrends in Neurosciences
Issue number8
StatePublished - Aug 1 1997

ASJC Scopus subject areas

  • Neuroscience(all)

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