Headache in thrombotic thrombocytopenic purpura: Two cases with pathophysiological considerations

David Bezov, Richard B. Lipton, Nikolai Podoltsev, Chi G. Zhao, Sait Ashina

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Headache is one of the most common neurological symptoms reported by patients with thrombotic thrombocytopenic purpura (TTP). Reports of headache characteristics in patients with TTP are rare. We report 2 cases of headache in a setting of TTP and review previous reports. Headache in TTP can have features in common with both migraine and tension-type headache. Although the pathophysiology of headache in TTP is not certain, platelet aggregation and activation may play a key role.

Original languageEnglish (US)
Pages (from-to)1060-1064
Number of pages5
JournalHeadache
Volume50
Issue number6
DOIs
StatePublished - 2010

Fingerprint

Thrombotic Thrombocytopenic Purpura
Headache
Tension-Type Headache
Platelet Activation
Migraine Disorders
Platelet Aggregation

Keywords

  • Headache
  • Headache characteristics
  • Platelet activation
  • Platelet aggregation
  • Thrombotic thrombocytopenic purpura

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Headache in thrombotic thrombocytopenic purpura : Two cases with pathophysiological considerations. / Bezov, David; Lipton, Richard B.; Podoltsev, Nikolai; Zhao, Chi G.; Ashina, Sait.

In: Headache, Vol. 50, No. 6, 2010, p. 1060-1064.

Research output: Contribution to journalArticle

Bezov, David ; Lipton, Richard B. ; Podoltsev, Nikolai ; Zhao, Chi G. ; Ashina, Sait. / Headache in thrombotic thrombocytopenic purpura : Two cases with pathophysiological considerations. In: Headache. 2010 ; Vol. 50, No. 6. pp. 1060-1064.
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