Growth-dependent expression of a cell surface glycoprotein

Lorenz Theilmann, Lucy Teicher, Carl S. Schildkraut, Richard J. Stockert

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

The expression of the hepatocellular membrane receptor for desialylated galactose-termining glycoproteins was studied during different proliferative stages of a human hepatoma cell line. Rapidly growing cells exhibited a reduced endocytotic rate of desialylated orsomucoid as compared to non-growing cells. This reduction was shown to be the consequence of a lower concentration of active cell-surface associated receptor protein in the dividing cells.

Original languageEnglish (US)
Pages (from-to)475-477
Number of pages3
JournalBBA - Molecular Cell Research
Volume762
Issue number3
DOIs
StatePublished - Jun 2 1983

Keywords

  • (Hepatoma cell)
  • Cell surface
  • Glycoprotein expression
  • Growth dependence

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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