Green fluorescent proteins are light-induced electron donors

Alexey M. Bogdanov, Alexander S. Mishin, Ilia V. Yampolsky, Vsevolod V. Belousov, Dmitriy M. Chudakov, Fedor V. Subach, Vladislav Verkhusha, Sergey Lukyanov, Konstantin A. Lukyanov

Research output: Contribution to journalArticle

128 Citations (Scopus)

Abstract

Proteins of the green fluorescent protein (GFP) family are well known owing to their unique biochemistry and extensive use as in vivo markers. We discovered that GFPs of diverse origins can act as light-induced electron donors in photochemical reactions with various electron acceptors, including biologically relevant ones. Moreover, via green-to-red GFP photoconversion, this process can be observed in living cells without additional treatment.

Original languageEnglish (US)
Pages (from-to)459-461
Number of pages3
JournalNature Chemical Biology
Volume5
Issue number7
DOIs
StatePublished - Jul 2009

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Green Fluorescent Proteins
Electrons
Light
Biochemistry
Proteins
red fluorescent protein

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology

Cite this

Bogdanov, A. M., Mishin, A. S., Yampolsky, I. V., Belousov, V. V., Chudakov, D. M., Subach, F. V., ... Lukyanov, K. A. (2009). Green fluorescent proteins are light-induced electron donors. Nature Chemical Biology, 5(7), 459-461. https://doi.org/10.1038/nchembio.174

Green fluorescent proteins are light-induced electron donors. / Bogdanov, Alexey M.; Mishin, Alexander S.; Yampolsky, Ilia V.; Belousov, Vsevolod V.; Chudakov, Dmitriy M.; Subach, Fedor V.; Verkhusha, Vladislav; Lukyanov, Sergey; Lukyanov, Konstantin A.

In: Nature Chemical Biology, Vol. 5, No. 7, 07.2009, p. 459-461.

Research output: Contribution to journalArticle

Bogdanov, AM, Mishin, AS, Yampolsky, IV, Belousov, VV, Chudakov, DM, Subach, FV, Verkhusha, V, Lukyanov, S & Lukyanov, KA 2009, 'Green fluorescent proteins are light-induced electron donors', Nature Chemical Biology, vol. 5, no. 7, pp. 459-461. https://doi.org/10.1038/nchembio.174
Bogdanov AM, Mishin AS, Yampolsky IV, Belousov VV, Chudakov DM, Subach FV et al. Green fluorescent proteins are light-induced electron donors. Nature Chemical Biology. 2009 Jul;5(7):459-461. https://doi.org/10.1038/nchembio.174
Bogdanov, Alexey M. ; Mishin, Alexander S. ; Yampolsky, Ilia V. ; Belousov, Vsevolod V. ; Chudakov, Dmitriy M. ; Subach, Fedor V. ; Verkhusha, Vladislav ; Lukyanov, Sergey ; Lukyanov, Konstantin A. / Green fluorescent proteins are light-induced electron donors. In: Nature Chemical Biology. 2009 ; Vol. 5, No. 7. pp. 459-461.
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