Glycoproteins and glycopeptides in the chromaffin granule membrane

L. Giorgio Roda, Emily P. Slater, Ruth A. Hogue-Angeletti

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The glycoproteins and glycopeptides of adrenal chromaffin granule membranes have been analyzed by gel filtration, electrophoresis, and amino acid analysis. It has been found that almost all of the polypeptides present in the membrane are glycoproteins. Indeed, most of these possess sugar specificities which permit binding to concanavalin A-Sepharose. A new set of low-molecular-weight glycopeptides was found. There is an inverse correlation between carbohydrate content and polypeptide molecular weight.

Original languageEnglish (US)
Pages (from-to)1243-1250
Number of pages8
JournalNeurochemical Research
Volume5
Issue number12
DOIs
StatePublished - Dec 1 1980

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

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