Glucose: A novel regulator of notch signaling

Research output: Contribution to journalReview article

4 Scopus citations


Notch signaling regulates cell fate during the development of many tissues. A new Drosophila mutant, rumi, is defective in Notch signaling because it cannot add glucose to serine in epidermal growth factor repeats of Notch extracellular domain. This is the first biological role for glucose covalently attached to a cell surface signaling receptor.

Original languageEnglish (US)
Pages (from-to)210-213
Number of pages4
JournalACS Chemical Biology
Issue number4
StatePublished - Apr 18 2008


ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine

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