GenPlay Multi-Genome, a tool to compare and analyze multiple human genomes in a graphical interface

Julien Lajugie, Nicolas Fourel, Eric E. Bouhassira

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Summary: Parallel visualization of multiple individual human genomes is a complex endeavor that is rapidly gaining importance with the increasing number of personal, phased and cancer genomes that are being generated. It requires the display of variants such as SNPs, indels and structural variants that are unique to specific genomes and the introduction of multiple overlapping gaps in the reference sequence. Here, we describe GenPlay Multi-Genome, an application specifically written to visualize and analyze multiple human genomes in parallel. GenPlay Multi-Genome is ideally suited for the comparison of allele-specific expression and functional genomic data obtained from multiple phased genomes in a graphical interface with access to multiple-track operation. It also allows the analysis of data that have been aligned to custom genomes rather than to a standard reference and can be used as a variant calling format file browser and as a tool to compare different genome assembly, such as hg19 and hg38. Availability and implementation: GenPlay is available under the GNU public license (GPL-3) from http://genplay.einstein.yu.edu. The source code is available at https://github.com/JulienLajugie/GenPlay Contact: or julien.lajugie@gmail.com Supplementary information: Supplementary data are available at Bioinformatics online.

Original languageEnglish (US)
Pages (from-to)109-111
Number of pages3
JournalBioinformatics
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2015

Fingerprint

Human Genome
Genome
Genes
Licensure
Functional Genomics
Graphics
Human
Computational Biology
Single Nucleotide Polymorphism
Bioinformatics
Alleles
Albert Einstein
Overlapping
Display
Cancer
Visualization
Availability
Display devices
Contact
Neoplasms

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Computational Theory and Mathematics
  • Computer Science Applications
  • Computational Mathematics
  • Statistics and Probability

Cite this

GenPlay Multi-Genome, a tool to compare and analyze multiple human genomes in a graphical interface. / Lajugie, Julien; Fourel, Nicolas; Bouhassira, Eric E.

In: Bioinformatics, Vol. 31, No. 1, 01.01.2015, p. 109-111.

Research output: Contribution to journalArticle

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