Genomics approaches to drug discovery

John F. Reidhaar-Olson, Brian K. Rhees, Juergen Hammer

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

New approaches to drug discovery have come about in recent years as a result of important advances in genomics and bioinformatics. The availability of genome-scale sequence data, the development of new tools for high-throughput gene expression monitoring, and improvements in the ability to analyze large data sets have revolutionized the field. In this article, we discuss three applications of genomics data in the drug discovery process: target discovery, prodrug strategies, and vaccine development.

Original languageEnglish (US)
Pages (from-to)110-119
Number of pages10
JournalJournal of Cellular Biochemistry
Volume84
Issue numberSUPPL. 37
DOIs
Publication statusPublished - Dec 1 2001

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Keywords

  • Bioinformatics
  • Epitope
  • Gene expression
  • Genomics
  • Target identification

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Cite this

Reidhaar-Olson, J. F., Rhees, B. K., & Hammer, J. (2001). Genomics approaches to drug discovery. Journal of Cellular Biochemistry, 84(SUPPL. 37), 110-119. https://doi.org/10.1002/jcb.10072