GENETIC MARKER FOR INSULIN-DEPENDENT DIABETES MELLITUS

D. Raum; C. A. Alper; R. Stein; K. H. Gabbay

doi:10.1016/S0140-6736(79)91895-6

GENETIC MARKER FOR INSULIN-DEPENDENT DIABETES MELLITUS

D. Raum, C. A. Alper, R. Stein, K. H. Gabbay

Research output: Contribution to journal › Article › peer-review

82 Scopus citations

Abstract

A rare genetic type (Bf F1) of properdin factor B is found in 22·6% of patients with insulin-dependent diabetes mellitus but in only 1·9% of the general population, yielding a relative risk of 15·0. This indicates that a genetic locus for insulin-dependent diabetes mellitus is very close on chromosome 6 to Bf, and that Bf F1 is a marker for nearly 1 out of 4 insulin-dependent diabetic patients.

Original language	English (US)
Pages (from-to)	1208-1210
Number of pages	3
Journal	The Lancet
Volume	313
Issue number	8128
DOIs	https://doi.org/10.1016/S0140-6736(79)91895-6
State	Published - Jun 9 1979
Externally published	Yes

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0140-6736(79)91895-6

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title = "GENETIC MARKER FOR INSULIN-DEPENDENT DIABETES MELLITUS",

abstract = "A rare genetic type (Bf F1) of properdin factor B is found in 22·6% of patients with insulin-dependent diabetes mellitus but in only 1·9% of the general population, yielding a relative risk of 15·0. This indicates that a genetic locus for insulin-dependent diabetes mellitus is very close on chromosome 6 to Bf, and that Bf F1 is a marker for nearly 1 out of 4 insulin-dependent diabetic patients.",

author = "D. Raum and Alper, {C. A.} and R. Stein and Gabbay, {K. H.}",

note = "Funding Information: vironmental Health Sciences grant no. 2P30 ES00928 06; National Institute of Arthritis, Metabolism, and Digestive Diseases grant no. 17702; and National Heart, Lung, and Blood Institute grant 21756. Funding Information: Supported by National Institutes of Health National Institute of En-",

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AU - Alper, C. A.

AU - Stein, R.

AU - Gabbay, K. H.

N1 - Funding Information: vironmental Health Sciences grant no. 2P30 ES00928 06; National Institute of Arthritis, Metabolism, and Digestive Diseases grant no. 17702; and National Heart, Lung, and Blood Institute grant 21756. Funding Information: Supported by National Institutes of Health National Institute of En-

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AB - A rare genetic type (Bf F1) of properdin factor B is found in 22·6% of patients with insulin-dependent diabetes mellitus but in only 1·9% of the general population, yielding a relative risk of 15·0. This indicates that a genetic locus for insulin-dependent diabetes mellitus is very close on chromosome 6 to Bf, and that Bf F1 is a marker for nearly 1 out of 4 insulin-dependent diabetic patients.

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GENETIC MARKER FOR INSULIN-DEPENDENT DIABETES MELLITUS

Abstract

ASJC Scopus subject areas

UN SDGs

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