GENETIC MARKER FOR INSULIN-DEPENDENT DIABETES MELLITUS

D. Raum, C. A. Alper, R. Stein, K. H. Gabbay

Research output: Contribution to journalArticle

81 Scopus citations

Abstract

A rare genetic type (Bf F1) of properdin factor B is found in 22·6% of patients with insulin-dependent diabetes mellitus but in only 1·9% of the general population, yielding a relative risk of 15·0. This indicates that a genetic locus for insulin-dependent diabetes mellitus is very close on chromosome 6 to Bf, and that Bf F1 is a marker for nearly 1 out of 4 insulin-dependent diabetic patients.

Original languageEnglish (US)
Pages (from-to)1208-1210
Number of pages3
JournalThe Lancet
Volume313
Issue number8128
DOIs
StatePublished - Jun 9 1979
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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