Genetic control of the susceptibility of C3HeB/FeJ mice to Salmonella typhimurium is regulated by a locus distinct from known salmonella response genes

A. D. O'Brien, David L. Rosenstreich

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11 Citations (Scopus)

Abstract

The relationship between the gene(s) responsible for the susceptibility of C3HeB/FeJ mice to the other known S. typhimurium resistance gene loci was investigated using a gene complementation analysis. C3HeB/FeJ female mice were bred to several other susceptible inbred strains and the F1 hybrid progeny were tested for S. typhimurium susceptibility. The findings indicate that the C3Heb/FeJ susceptibility gene is distinct from these other resistance gene loci.

Original languageEnglish (US)
Pages (from-to)2613-2615
Number of pages3
JournalJournal of Immunology
Volume131
Issue number6
StatePublished - 1983
Externally publishedYes

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Salmonella typhimurium
Genetic Predisposition to Disease
Salmonella
Genes

ASJC Scopus subject areas

  • Immunology

Cite this

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AB - The relationship between the gene(s) responsible for the susceptibility of C3HeB/FeJ mice to the other known S. typhimurium resistance gene loci was investigated using a gene complementation analysis. C3HeB/FeJ female mice were bred to several other susceptible inbred strains and the F1 hybrid progeny were tested for S. typhimurium susceptibility. The findings indicate that the C3Heb/FeJ susceptibility gene is distinct from these other resistance gene loci.

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