Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae

Paul F. Riska; Andrei Kutlin; Patrick Ajiboye; Arnold Cua; Patricia M. Roblin; Margaret R. Hammerschlag

doi:10.1128/AAC.48.9.3586-3590.2004

Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae

Paul F. Riska, Andrei Kutlin, Patrick Ajiboye, Arnold Cua, Patricia M. Roblin, Margaret R. Hammerschlag

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Three clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C, pneumoniae isolates. No macrolide resistance was obtained in vitro.

Original language	English (US)
Pages (from-to)	3586-3590
Number of pages	5
Journal	Antimicrobial agents and chemotherapy
Volume	48
Issue number	9
DOIs	https://doi.org/10.1128/AAC.48.9.3586-3590.2004
State	Published - Sep 2004
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/AAC.48.9.3586-3590.2004

Cite this

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title = "Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae",

abstract = "Three clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C, pneumoniae isolates. No macrolide resistance was obtained in vitro.",

author = "Riska, {Paul F.} and Andrei Kutlin and Patrick Ajiboye and Arnold Cua and Roblin, {Patricia M.} and Hammerschlag, {Margaret R.}",

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AU - Riska, Paul F.

AU - Kutlin, Andrei

AU - Ajiboye, Patrick

AU - Cua, Arnold

AU - Roblin, Patricia M.

AU - Hammerschlag, Margaret R.

PY - 2004/9

Y1 - 2004/9

N2 - Three clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C, pneumoniae isolates. No macrolide resistance was obtained in vitro.

AB - Three clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C, pneumoniae isolates. No macrolide resistance was obtained in vitro.

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DO - 10.1128/AAC.48.9.3586-3590.2004

M3 - Article

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AN - SCOPUS:4344591552

SN - 0066-4804

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JO - Antimicrobial Agents and Chemotherapy

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IS - 9

ER -

Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae

Abstract

ASJC Scopus subject areas

UN SDGs

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