Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae

Paul F. Riska, Andrei Kutlin, Patrick Ajiboye, Arnold Cua, Patricia M. Roblin, Margaret R. Hammerschlag

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Three clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C, pneumoniae isolates. No macrolide resistance was obtained in vitro.

Original languageEnglish (US)
Pages (from-to)3586-3590
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume48
Issue number9
DOIs
StatePublished - Sep 2004
Externally publishedYes

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Chlamydophila pneumoniae
Macrolides
Azithromycin
Microbial Drug Resistance
Pneumonia
In Vitro Techniques

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae. / Riska, Paul F.; Kutlin, Andrei; Ajiboye, Patrick; Cua, Arnold; Roblin, Patricia M.; Hammerschlag, Margaret R.

In: Antimicrobial Agents and Chemotherapy, Vol. 48, No. 9, 09.2004, p. 3586-3590.

Research output: Contribution to journalArticle

Riska, Paul F. ; Kutlin, Andrei ; Ajiboye, Patrick ; Cua, Arnold ; Roblin, Patricia M. ; Hammerschlag, Margaret R. / Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae. In: Antimicrobial Agents and Chemotherapy. 2004 ; Vol. 48, No. 9. pp. 3586-3590.
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