Genetic and culture-based approaches for detecting macrolide resistance in Chlamydia pneumoniae

Paul F. Riska, Andrei Kutlin, Patrick Ajiboye, Arnold Cua, Patricia M. Roblin, Margaret R. Hammerschlag

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Three clinical Chlamydia pneumoniae isolates for which the MIC of azithromycin increased after treatment were investigated for genetic evidence of macrolide resistance. Attempts to induce antibiotic resistance in vitro were made. No genetic mechanism was identified for the phenotypic change in these C, pneumoniae isolates. No macrolide resistance was obtained in vitro.

Original languageEnglish (US)
Pages (from-to)3586-3590
Number of pages5
JournalAntimicrobial Agents and Chemotherapy
Volume48
Issue number9
DOIs
StatePublished - Sep 1 2004
Externally publishedYes

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ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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