Genetic analysis in young-age-of-onset graves' disease reveals new susceptibility loci

Rosalind S. Brown, Angela Lombardi, Alia Hasham, David A. Greenberg, Joshua Gordon, Erlinda Concepcion, Sara S. Hammerstad, Vaneet Lotay, Weijia Zhang, Yaron Tomer

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Context: Genetic and environmental factors play an essential role in the pathogenesis of Graves' Disease (GD). Children with GD have less exposure time to environmental factors and therefore are believed to harbor stronger genetic susceptibility than adults. Objective: The aim of the study was to identify susceptibility loci that predispose to GD in patients with young-age-of-onset (YAO) GD. Setting and Design: One hundred six patients with YAO GD (onset

Original languageEnglish (US)
JournalJournal of Clinical Endocrinology and Metabolism
Volume99
Issue number7
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Graves Disease
Age of Onset
Genetic Predisposition to Disease
Ports and harbors

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Endocrinology
  • Biochemistry, medical
  • Endocrinology, Diabetes and Metabolism

Cite this

Genetic analysis in young-age-of-onset graves' disease reveals new susceptibility loci. / Brown, Rosalind S.; Lombardi, Angela; Hasham, Alia; Greenberg, David A.; Gordon, Joshua; Concepcion, Erlinda; Hammerstad, Sara S.; Lotay, Vaneet; Zhang, Weijia; Tomer, Yaron.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 99, No. 7, 2014.

Research output: Contribution to journalArticle

Brown, Rosalind S. ; Lombardi, Angela ; Hasham, Alia ; Greenberg, David A. ; Gordon, Joshua ; Concepcion, Erlinda ; Hammerstad, Sara S. ; Lotay, Vaneet ; Zhang, Weijia ; Tomer, Yaron. / Genetic analysis in young-age-of-onset graves' disease reveals new susceptibility loci. In: Journal of Clinical Endocrinology and Metabolism. 2014 ; Vol. 99, No. 7.
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