Abstract
The potential clinical advantages of a gene transfer therapy-based approach to treatment of genitourinary smooth muscle-based disorders are several: potential single therapy for restoration of normal bladder or erectile function; eliminating the need for daily medication; use in combination with other therapies to reduce dose requirements and side effects; and development of mechanism-based, patient-specific treatment approaches. With the safe administration of hMax-K to men with erectile dysfunction in the first human phase 1 trial and the initiation of the phase 1 trial of hMaxi-K for patients who have detrusor overactivity, we have entered an exciting new era in the development of safe enduring therapies for genitourinary disorders.
Original language | English (US) |
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Pages (from-to) | 619-630 |
Number of pages | 12 |
Journal | Urologic Clinics of North America |
Volume | 34 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2007 |
ASJC Scopus subject areas
- Urology