Gene therapy and solid-organ transplantation

Enver Akalin, Jonathan S. Bromberg

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Recent developments in transplantation medicine improved the short- and long-term survival of solid-organ transplantation. However, chronic allograft rejection, the side effects of the long-term immunosuppressive treatment, and organ shortage are still the major obstacles to achieving long-term survival. Gene therapy has the potential to meet these challenges and has unique advantages in transplantation. In this review we summarize the studies using gene therapy in solid-organ transplantation.

Original languageEnglish (US)
Pages (from-to)S56-S60
JournalKidney international
Volume61
Issue numberSUPPL. 1
DOIs
StatePublished - 2002
Externally publishedYes

Keywords

  • Allograft
  • Gene therapy
  • Rejection
  • Transplantation
  • Xenotransplantation

ASJC Scopus subject areas

  • Nephrology

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