Abstract
Gene targeting by homologous recombination is a genetic tool that permits modification of cellular genes in a precise and predetermined fashion. The methodologies that are currently available permit gene targeting at high efficiency and fidelity. New developments promise large-scale modification of the mammalian genome using these techniques.
Original language | English (US) |
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Pages (from-to) | 577-582 |
Number of pages | 6 |
Journal | Current Opinion in Biotechnology |
Volume | 4 |
Issue number | 5 |
DOIs | |
State | Published - Oct 1993 |
ASJC Scopus subject areas
- Biotechnology
- Bioengineering
- Biomedical Engineering