Gene targeting in mammalian cells by homologous recombination

Bernice E. Morrow, Raju Kucherlapati

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Gene targeting by homologous recombination is a genetic tool that permits modification of cellular genes in a precise and predetermined fashion. The methodologies that are currently available permit gene targeting at high efficiency and fidelity. New developments promise large-scale modification of the mammalian genome using these techniques.

Original languageEnglish (US)
Pages (from-to)577-582
Number of pages6
JournalCurrent Opinion in Biotechnology
Volume4
Issue number5
DOIs
StatePublished - 1993

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Gene Targeting
Homologous Recombination
Genes
Cells
Genome

ASJC Scopus subject areas

  • Biochemistry
  • Biotechnology
  • Bioengineering

Cite this

Gene targeting in mammalian cells by homologous recombination. / Morrow, Bernice E.; Kucherlapati, Raju.

In: Current Opinion in Biotechnology, Vol. 4, No. 5, 1993, p. 577-582.

Research output: Contribution to journalArticle

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