Gene regulation: The HSP70 gene jumps when shocked

Maria Vera, Robert H. Singer

Research output: Contribution to journalShort survey

2 Scopus citations

Abstract

Limited chromosome mobility has been observed in mammalian interphase nuclei. Live imaging shows unidirectional and actin-dependent movement of HSP70 loci towards speckles upon heat shock, resulting in enhanced transcription. This adds further impetus to understanding compartmentalization of function in the nucleus.

Original languageEnglish (US)
Pages (from-to)R396-R398
JournalCurrent Biology
Volume24
Issue number10
DOIs
StatePublished - May 19 2014

    Fingerprint

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this