Abstract
Obesity and gastroesophageal reflux disease (GERD) are common conditions that both have been on the rise. The direct relationship between GERD symptoms and obesity has been demonstrated in many epidemiologic studies. The pathophysiological mechanisms that cause this relationship have also been proposed and include decreased pressure of the lower esophageal sphincter, increased episodes of transient lower esophageal sphincter relaxations, increased intra-abdominal and intragastric pressures, and hiatal hernia. Medical treatment with either weight loss or proton pump inhibitors is effective at treating GERD symptoms in the obese. Antireflux surgery in patients with elevated body mass index has been described with varied results. Bariatric procedures have also been evaluated for their effect on GERD, with laparoscopic gastric bypass offering the best results when compared with laparoscopic sleeve gastrectomy or laparoscopic adjustable gastric banding. Those with GERD and obesity may benefit from bariatric surgery, and referral for it should be considered.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 83-88 |
| Number of pages | 6 |
| Journal | Techniques in Gastrointestinal Endoscopy |
| Volume | 17 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 1 2015 |
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Keywords
- Adjustable gastric band
- Gastric bypass
- Lower esophageal sphincter
- Sleeve gastrectomy
- Weight loss
ASJC Scopus subject areas
- Gastroenterology
- Radiology Nuclear Medicine and imaging
Cite this
Gastroesophageal reflux disease in the obese. / Camacho, Diego; LeMasters, Patrick E.
In: Techniques in Gastrointestinal Endoscopy, Vol. 17, No. 2, 01.04.2015, p. 83-88.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Gastroesophageal reflux disease in the obese
AU - Camacho, Diego
AU - LeMasters, Patrick E.
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Obesity and gastroesophageal reflux disease (GERD) are common conditions that both have been on the rise. The direct relationship between GERD symptoms and obesity has been demonstrated in many epidemiologic studies. The pathophysiological mechanisms that cause this relationship have also been proposed and include decreased pressure of the lower esophageal sphincter, increased episodes of transient lower esophageal sphincter relaxations, increased intra-abdominal and intragastric pressures, and hiatal hernia. Medical treatment with either weight loss or proton pump inhibitors is effective at treating GERD symptoms in the obese. Antireflux surgery in patients with elevated body mass index has been described with varied results. Bariatric procedures have also been evaluated for their effect on GERD, with laparoscopic gastric bypass offering the best results when compared with laparoscopic sleeve gastrectomy or laparoscopic adjustable gastric banding. Those with GERD and obesity may benefit from bariatric surgery, and referral for it should be considered.
AB - Obesity and gastroesophageal reflux disease (GERD) are common conditions that both have been on the rise. The direct relationship between GERD symptoms and obesity has been demonstrated in many epidemiologic studies. The pathophysiological mechanisms that cause this relationship have also been proposed and include decreased pressure of the lower esophageal sphincter, increased episodes of transient lower esophageal sphincter relaxations, increased intra-abdominal and intragastric pressures, and hiatal hernia. Medical treatment with either weight loss or proton pump inhibitors is effective at treating GERD symptoms in the obese. Antireflux surgery in patients with elevated body mass index has been described with varied results. Bariatric procedures have also been evaluated for their effect on GERD, with laparoscopic gastric bypass offering the best results when compared with laparoscopic sleeve gastrectomy or laparoscopic adjustable gastric banding. Those with GERD and obesity may benefit from bariatric surgery, and referral for it should be considered.
KW - Adjustable gastric band
KW - Gastric bypass
KW - Lower esophageal sphincter
KW - Sleeve gastrectomy
KW - Weight loss
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U2 - 10.1016/j.tgie.2015.02.009
DO - 10.1016/j.tgie.2015.02.009
M3 - Article
VL - 17
SP - 83
EP - 88
JO - Techniques in Gastrointestinal Endoscopy
JF - Techniques in Gastrointestinal Endoscopy
SN - 1096-2883
IS - 2
ER -