Gastroesophageal reflux disease in the obese

Diego R. Camacho, Patrick E. LeMasters

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Obesity and gastroesophageal reflux disease (GERD) are common conditions that both have been on the rise. The direct relationship between GERD symptoms and obesity has been demonstrated in many epidemiologic studies. The pathophysiological mechanisms that cause this relationship have also been proposed and include decreased pressure of the lower esophageal sphincter, increased episodes of transient lower esophageal sphincter relaxations, increased intra-abdominal and intragastric pressures, and hiatal hernia. Medical treatment with either weight loss or proton pump inhibitors is effective at treating GERD symptoms in the obese. Antireflux surgery in patients with elevated body mass index has been described with varied results. Bariatric procedures have also been evaluated for their effect on GERD, with laparoscopic gastric bypass offering the best results when compared with laparoscopic sleeve gastrectomy or laparoscopic adjustable gastric banding. Those with GERD and obesity may benefit from bariatric surgery, and referral for it should be considered.

Original languageEnglish (US)
Pages (from-to)83-88
Number of pages6
JournalTechniques in Gastrointestinal Endoscopy
Volume17
Issue number2
DOIs
Publication statusPublished - Apr 1 2015

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Keywords

  • Adjustable gastric band
  • Gastric bypass
  • Lower esophageal sphincter
  • Sleeve gastrectomy
  • Weight loss

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

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