Gap junctions in the brain

where, what type, how many and why?

Rolf Dermietzel, David C. Spray

Research output: Contribution to journalArticle

421 Citations (Scopus)

Abstract

Gap junctions represent well-documented means of intercellular communication in various tissues, including the brain, where they function as portals allowing the exchange of electrolytes, second messengers and metabolites between cells. In view of the enormous recent surge of information dealing with the cellular and molecular biology of gap junctions in non-nervous tissue, as well as current interest in the cell biology of glia, this review is intended to provide an overview of the molecular and functional implications of gap-junction-mediated intercellular communication in the nervous system.

Original languageEnglish (US)
Pages (from-to)186-192
Number of pages7
JournalTrends in Neurosciences
Volume16
Issue number5
DOIs
StatePublished - 1993

Fingerprint

Gap Junctions
Cell Biology
Brain
Second Messenger Systems
Neuroglia
Nervous System
Electrolytes
Molecular Biology

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Gap junctions in the brain : where, what type, how many and why? / Dermietzel, Rolf; Spray, David C.

In: Trends in Neurosciences, Vol. 16, No. 5, 1993, p. 186-192.

Research output: Contribution to journalArticle

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