TY - JOUR
T1 - Gap junctions in the brain
T2 - where, what type, how many and why?
AU - Dermietzel, Rolf
AU - Spray, David C.
PY - 1993/5
Y1 - 1993/5
N2 - Gap junctions represent well-documented means of intercellular communication in various tissues, including the brain, where they function as portals allowing the exchange of electrolytes, second messengers and metabolites between cells. In view of the enormous recent surge of information dealing with the cellular and molecular biology of gap junctions in non-nervous tissue, as well as current interest in the cell biology of glia, this review is intended to provide an overview of the molecular and functional implications of gap-junction-mediated intercellular communication in the nervous system.
AB - Gap junctions represent well-documented means of intercellular communication in various tissues, including the brain, where they function as portals allowing the exchange of electrolytes, second messengers and metabolites between cells. In view of the enormous recent surge of information dealing with the cellular and molecular biology of gap junctions in non-nervous tissue, as well as current interest in the cell biology of glia, this review is intended to provide an overview of the molecular and functional implications of gap-junction-mediated intercellular communication in the nervous system.
UR - http://www.scopus.com/inward/record.url?scp=0027410499&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027410499&partnerID=8YFLogxK
U2 - 10.1016/0166-2236(93)90151-B
DO - 10.1016/0166-2236(93)90151-B
M3 - Review article
C2 - 7685944
AN - SCOPUS:0027410499
SN - 0166-2236
VL - 16
SP - 186
EP - 192
JO - Trends in Neurosciences
JF - Trends in Neurosciences
IS - 5
ER -