Cell pairs from late cleavage and early blastula Ambystoma mexicanum embryos were found to be electrotonically coupled. Thin‐section electron microscopy revealed typical gap junctions between the cells. Freeze‐fracture electron microscopy showed the gap junctions to be comprised of aggregations of 8.5‐nm P‐face particles and corresponding E‐face pits. The conductance of the amphibian embryonic gap junction is known to be voltage‐dependent, but no obvious gating structure was resolved by these morphological techniques.
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