TY - JOUR
T1 - Gamma and the Coordination of Spiking Activity in Early Visual Cortex
AU - Jia, Xiaoxuan
AU - Tanabe, Seiji
AU - Kohn, Adam
N1 - Funding Information:
This work was supported by grants from the National Institutes of Health (EY016774 and P30HD071593) and Research to Prevent Blindness. We thank Douglas McLelland and Steve Gotts for comments on an earlier version of this manuscript. We thank Amin Zandvakili for help with V1-V2 recordings and analysis.
PY - 2013/2/20
Y1 - 2013/2/20
N2 - Gamma components of the local field potential (LFP) are elevated during cognitive and perceptual processes. It has been suggested that gamma power indicates the strength of neuronal population synchrony, which influences the relaying of signals between cortical areas. However, the relationship between coordinated spiking activity and gamma remains unclear, and the influence on corticocortical signaling largely untested. We investigated these issues by recording from neuronal populations in areas V1 and V2 of anesthetized macaque monkeys. We found that visual stimuli that induce a strong, coherent gamma rhythm result in enhanced pairwise and higher-order V1 synchrony. This is associated with stronger coupling of V1-V2 spiking activity, in a retinotopically specific manner. Coupling is more strongly related to the gamma modulation of V1 firing than to the downstream V2 rhythm. Our results thus show that elevated gamma power is associated with stronger coordination of spiking activity both within and between cortical areas
AB - Gamma components of the local field potential (LFP) are elevated during cognitive and perceptual processes. It has been suggested that gamma power indicates the strength of neuronal population synchrony, which influences the relaying of signals between cortical areas. However, the relationship between coordinated spiking activity and gamma remains unclear, and the influence on corticocortical signaling largely untested. We investigated these issues by recording from neuronal populations in areas V1 and V2 of anesthetized macaque monkeys. We found that visual stimuli that induce a strong, coherent gamma rhythm result in enhanced pairwise and higher-order V1 synchrony. This is associated with stronger coupling of V1-V2 spiking activity, in a retinotopically specific manner. Coupling is more strongly related to the gamma modulation of V1 firing than to the downstream V2 rhythm. Our results thus show that elevated gamma power is associated with stronger coordination of spiking activity both within and between cortical areas
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U2 - 10.1016/j.neuron.2012.12.036
DO - 10.1016/j.neuron.2012.12.036
M3 - Article
C2 - 23439127
AN - SCOPUS:84874279023
SN - 0896-6273
VL - 77
SP - 762
EP - 774
JO - Neuron
JF - Neuron
IS - 4
ER -