Abstract
Anti-vascular endothelial growth factor (VEGF) cancer immunotherapy targets angiogenesis but development of resistance in patients is common. In this issue of Cell, Croci et al. identify a complex set of mechanisms by which galectin-1 prolongs cell-surface retention of VEGF receptor 2 (VEGFR2) and stimulates VEGF-independent tumor angiogenesis.
Original language | English (US) |
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Pages (from-to) | 625-626 |
Number of pages | 2 |
Journal | Cell |
Volume | 156 |
Issue number | 4 |
DOIs | |
State | Published - Feb 13 2014 |
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)