GABA receptors, progesterone and premenstrual dysphoric disorder

Inger Sundström Poromaa; S. Smith; M. Gulinello

doi:10.1007/s00737-002-0147-1

GABA receptors, progesterone and premenstrual dysphoric disorder

Inger Sundström Poromaa, S. Smith, M. Gulinello

Research output: Contribution to journal › Article › peer-review

109 Scopus citations

Abstract

Premenstrual dysphoric disorder (PMDD) is characterized by depression, anxiety and other affective symptoms which recur in the luteal phase of the menstrual cycle. Evidence from animal models of depression and anxiety indicate the importance of neuroactive steroid hormones and the GABA_A receptor in the etiology and potential treatment of mood disorders. These data are reviewed in the light of human clinical studies and specific animal models of PMDD.

Original language	English (US)
Pages (from-to)	23-41
Number of pages	19
Journal	Archives of Women's Mental Health
Volume	6
Issue number	1
DOIs	https://doi.org/10.1007/s00737-002-0147-1
State	Published - Feb 2003
Externally published	Yes

Keywords

Allopregnanolone
Animal model
Anxiety
Benzodiazepine
Depression
GABA
GABAR subunit
Human
Mood
Neurosteroid
Premenstrual dysphoric disorder PMDD
Progesterone
Stress

ASJC Scopus subject areas

Obstetrics and Gynecology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s00737-002-0147-1

Cite this

@article{3f1cbee1209d451380dd5fda7917ac74,

title = "GABA receptors, progesterone and premenstrual dysphoric disorder",

abstract = "Premenstrual dysphoric disorder (PMDD) is characterized by depression, anxiety and other affective symptoms which recur in the luteal phase of the menstrual cycle. Evidence from animal models of depression and anxiety indicate the importance of neuroactive steroid hormones and the GABAA receptor in the etiology and potential treatment of mood disorders. These data are reviewed in the light of human clinical studies and specific animal models of PMDD.",

keywords = "Allopregnanolone, Animal model, Anxiety, Benzodiazepine, Depression, GABA, GABAR subunit, Human, Mood, Neurosteroid, Premenstrual dysphoric disorder PMDD, Progesterone, Stress",

author = "{Sundstr{\"o}m Poromaa}, Inger and S. Smith and M. Gulinello",

year = "2003",

month = feb,

doi = "10.1007/s00737-002-0147-1",

language = "English (US)",

volume = "6",

pages = "23--41",

journal = "Archives of Women's Mental Health",

issn = "1434-1816",

publisher = "Springer Wien",

number = "1",

}

TY - JOUR

T1 - GABA receptors, progesterone and premenstrual dysphoric disorder

AU - Sundström Poromaa, Inger

AU - Smith, S.

AU - Gulinello, M.

PY - 2003/2

Y1 - 2003/2

N2 - Premenstrual dysphoric disorder (PMDD) is characterized by depression, anxiety and other affective symptoms which recur in the luteal phase of the menstrual cycle. Evidence from animal models of depression and anxiety indicate the importance of neuroactive steroid hormones and the GABAA receptor in the etiology and potential treatment of mood disorders. These data are reviewed in the light of human clinical studies and specific animal models of PMDD.

AB - Premenstrual dysphoric disorder (PMDD) is characterized by depression, anxiety and other affective symptoms which recur in the luteal phase of the menstrual cycle. Evidence from animal models of depression and anxiety indicate the importance of neuroactive steroid hormones and the GABAA receptor in the etiology and potential treatment of mood disorders. These data are reviewed in the light of human clinical studies and specific animal models of PMDD.

KW - Allopregnanolone

KW - Animal model

KW - Anxiety

KW - Benzodiazepine

KW - Depression

KW - GABA

KW - GABAR subunit

KW - Human

KW - Mood

KW - Neurosteroid

KW - Premenstrual dysphoric disorder PMDD

KW - Progesterone

KW - Stress

UR - http://www.scopus.com/inward/record.url?scp=0037298949&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037298949&partnerID=8YFLogxK

U2 - 10.1007/s00737-002-0147-1

DO - 10.1007/s00737-002-0147-1

M3 - Article

C2 - 12715262

AN - SCOPUS:0037298949

SN - 1434-1816

VL - 6

SP - 23

EP - 41

JO - Archives of Women's Mental Health

JF - Archives of Women's Mental Health

IS - 1

ER -

GABA receptors, progesterone and premenstrual dysphoric disorder

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this