s Uncouples Hematopoietic Stem Cell Homing and Mobilization

Simón Méndez-Ferrer, Paul S. Frenette

Research output: Contribution to journalShort survey

7 Scopus citations

Abstract

Defects of hematopoietic stem cell adhesion or migration generally lead to reduced homing to, and enhanced mobilization from, the bone marrow. In a recent publication in Nature, Adams et al. (2009) demonstrate that the guanine-nucleotide-binding stimulatory α subunit (Gαs) can, unexpectedly, promote both phenomena.

Original languageEnglish (US)
Pages (from-to)379-380
Number of pages2
JournalCell Stem Cell
Volume4
Issue number5
DOIs
StatePublished - May 8 2009
Externally publishedYes

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ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Cell Biology

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