TY - JOUR
T1 - Gαs Uncouples Hematopoietic Stem Cell Homing and Mobilization
AU - Méndez-Ferrer, Simón
AU - Frenette, Paul S.
PY - 2009/5/8
Y1 - 2009/5/8
N2 - Defects of hematopoietic stem cell adhesion or migration generally lead to reduced homing to, and enhanced mobilization from, the bone marrow. In a recent publication in Nature, Adams et al. (2009) demonstrate that the guanine-nucleotide-binding stimulatory α subunit (Gαs) can, unexpectedly, promote both phenomena.
AB - Defects of hematopoietic stem cell adhesion or migration generally lead to reduced homing to, and enhanced mobilization from, the bone marrow. In a recent publication in Nature, Adams et al. (2009) demonstrate that the guanine-nucleotide-binding stimulatory α subunit (Gαs) can, unexpectedly, promote both phenomena.
UR - http://www.scopus.com/inward/record.url?scp=65349148444&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=65349148444&partnerID=8YFLogxK
U2 - 10.1016/j.stem.2009.04.009
DO - 10.1016/j.stem.2009.04.009
M3 - Short survey
C2 - 19427288
AN - SCOPUS:65349148444
SN - 1934-5909
VL - 4
SP - 379
EP - 380
JO - Cell Stem Cell
JF - Cell Stem Cell
IS - 5
ER -