Further observations on the effects of lead implantation in rat brains

Asao Hirano; Joseph A. Kochen

doi:10.1007/BF00684659

Further observations on the effects of lead implantation in rat brains

Asao Hirano, Joseph A. Kochen

Pathology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Lead pellets were implanted into the forebrains of adult rats. Various cytoplasmic inclusions were found in macrophages, astrocytes, pericytes and microglia. Certain macrophages and reactive astrocytes displayed intranuclear inclusions as well. The hypothalamus, in some of the animals, showed sponginess which proved to be the result of swollen axons.

Original language	English (US)
Pages (from-to)	87-93
Number of pages	7
Journal	Acta neuropathologica
Volume	34
Issue number	2
DOIs	https://doi.org/10.1007/BF00684659
State	Published - Jun 1976

Keywords

Axonal swelling
Intranuclear inclusions
Lead
Macrophages

ASJC Scopus subject areas

Pathology and Forensic Medicine
Clinical Neurology
Cellular and Molecular Neuroscience

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10.1007/BF00684659

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title = "Further observations on the effects of lead implantation in rat brains",

abstract = "Lead pellets were implanted into the forebrains of adult rats. Various cytoplasmic inclusions were found in macrophages, astrocytes, pericytes and microglia. Certain macrophages and reactive astrocytes displayed intranuclear inclusions as well. The hypothalamus, in some of the animals, showed sponginess which proved to be the result of swollen axons.",

keywords = "Axonal swelling, Intranuclear inclusions, Lead, Macrophages",

author = "Asao Hirano and Kochen, {Joseph A.}",

year = "1976",

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AU - Hirano, Asao

AU - Kochen, Joseph A.

PY - 1976/6

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AB - Lead pellets were implanted into the forebrains of adult rats. Various cytoplasmic inclusions were found in macrophages, astrocytes, pericytes and microglia. Certain macrophages and reactive astrocytes displayed intranuclear inclusions as well. The hypothalamus, in some of the animals, showed sponginess which proved to be the result of swollen axons.

KW - Axonal swelling

KW - Intranuclear inclusions

KW - Lead

KW - Macrophages

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ER -

Further observations on the effects of lead implantation in rat brains

Abstract

Keywords

ASJC Scopus subject areas

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