Functionally Relevant RNA Helicase Mutations in Familial and Sporadic Myeloid Malignancies

Iléana Antony-Debré, Ulrich G. Steidl

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In this issue of Cancer Cell, Polprasert and colleagues identified recurrent mutations in the DEAD/H-box RNA helicase gene DDX41 in familial and acquired cases of myelodsyplasia and acute myeloid leukemia. These mutations induce defects in RNA splicing and represent a new class of mutations in myeloid malignancies.

Original languageEnglish (US)
Pages (from-to)609-611
Number of pages3
JournalCancer Cell
Volume27
Issue number5
DOIs
StatePublished - May 11 2015

Fingerprint

RNA Helicases
Mutation
DEAD-box RNA Helicases
RNA Splicing
Neoplasms
Acute Myeloid Leukemia
Genes

ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology
  • Oncology
  • Medicine(all)

Cite this

Functionally Relevant RNA Helicase Mutations in Familial and Sporadic Myeloid Malignancies. / Antony-Debré, Iléana; Steidl, Ulrich G.

In: Cancer Cell, Vol. 27, No. 5, 11.05.2015, p. 609-611.

Research output: Contribution to journalArticle

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