In this issue of Cancer Cell, Polprasert and colleagues identified recurrent mutations in the DEAD/H-box RNA helicase gene DDX41 in familial and acquired cases of myelodsyplasia and acute myeloid leukemia. These mutations induce defects in RNA splicing and represent a new class of mutations in myeloid malignancies.
|Original language||English (US)|
|Number of pages||3|
|State||Published - May 11 2015|
ASJC Scopus subject areas
- Cell Biology
- Cancer Research