Functionalized main-group organometallics for organic synthesis

Paul Knochel; Eike Hupe; Wolfgang Dohle; David M. Lindsay; Véronique Bonnet; Guy Quéguiner; Andreas Boudier; Felix Kopp; Stéphane Demay; Naka Seidel; M. Isabel Calaza; Viet Anh Vu; Ioannis Sapountzis; Tanasri Bunlaksananusorn

doi:10.1351/pac200274010011

Functionalized main-group organometallics for organic synthesis

Paul Knochel, Eike Hupe, Wolfgang Dohle, David M. Lindsay, Véronique Bonnet, Guy Quéguiner, Andreas Boudier, Felix Kopp, Stéphane Demay, Naka Seidel, M. Isabel Calaza, Viet Anh Vu, Ioannis Sapountzis, Tanasri Bunlaksananusorn

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Highly functionalized Grignard-reagents can be easily obtained by an iodine-magnesim exchange reaction and further reacted with various electrophiles. Via a B-Zn exchange reaction, a formal Michael addition with umpolung of the reactivity can be achieved. Chiral phosphine ligands can be easily synthesized by a 2.3 sigmatropic rearrangement and used successfully in asymmetric synthesis.

Original language	English (US)
Pages (from-to)	11-17
Number of pages	7
Journal	Pure and Applied Chemistry
Volume	74
Issue number	1
DOIs	https://doi.org/10.1351/pac200274010011
State	Published - 2002
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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title = "Functionalized main-group organometallics for organic synthesis",

abstract = "Highly functionalized Grignard-reagents can be easily obtained by an iodine-magnesim exchange reaction and further reacted with various electrophiles. Via a B-Zn exchange reaction, a formal Michael addition with umpolung of the reactivity can be achieved. Chiral phosphine ligands can be easily synthesized by a 2.3 sigmatropic rearrangement and used successfully in asymmetric synthesis.",

author = "Paul Knochel and Eike Hupe and Wolfgang Dohle and Lindsay, {David M.} and V{\'e}ronique Bonnet and Guy Qu{\'e}guiner and Andreas Boudier and Felix Kopp and St{\'e}phane Demay and Naka Seidel and Calaza, {M. Isabel} and Vu, {Viet Anh} and Ioannis Sapountzis and Tanasri Bunlaksananusorn",

year = "2002",

doi = "10.1351/pac200274010011",

language = "English (US)",

volume = "74",

pages = "11--17",

journal = "Pure and Applied Chemistry",

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publisher = "IUPAC Secretariat",

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TY - JOUR

T1 - Functionalized main-group organometallics for organic synthesis

AU - Knochel, Paul

AU - Hupe, Eike

AU - Dohle, Wolfgang

AU - Lindsay, David M.

AU - Bonnet, Véronique

AU - Quéguiner, Guy

AU - Boudier, Andreas

AU - Kopp, Felix

AU - Demay, Stéphane

AU - Seidel, Naka

AU - Calaza, M. Isabel

AU - Vu, Viet Anh

AU - Sapountzis, Ioannis

AU - Bunlaksananusorn, Tanasri

PY - 2002

Y1 - 2002

N2 - Highly functionalized Grignard-reagents can be easily obtained by an iodine-magnesim exchange reaction and further reacted with various electrophiles. Via a B-Zn exchange reaction, a formal Michael addition with umpolung of the reactivity can be achieved. Chiral phosphine ligands can be easily synthesized by a 2.3 sigmatropic rearrangement and used successfully in asymmetric synthesis.

AB - Highly functionalized Grignard-reagents can be easily obtained by an iodine-magnesim exchange reaction and further reacted with various electrophiles. Via a B-Zn exchange reaction, a formal Michael addition with umpolung of the reactivity can be achieved. Chiral phosphine ligands can be easily synthesized by a 2.3 sigmatropic rearrangement and used successfully in asymmetric synthesis.

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U2 - 10.1351/pac200274010011

DO - 10.1351/pac200274010011

M3 - Article

AN - SCOPUS:0036291458

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VL - 74

SP - 11

EP - 17

JO - Pure and Applied Chemistry

JF - Pure and Applied Chemistry

IS - 1

ER -

Functionalized main-group organometallics for organic synthesis

Abstract

ASJC Scopus subject areas

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