Functional organization of neuronal and humoral signals regulating feeding behavior

Gary J. Schwartz, Lori M. Zeltser

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Energy homeostasis-ensuring that energy availability matches energy requirements-is essential for survival. One way that energy balance is achieved is through coordinated action of neural and neuroendocrine feeding circuits, which promote energy intake when energy supply is limited. Feeding behavior engages multiple somatic and visceral tissues distributed throughout the body-contraction of skeletal and smooth muscles in the head and along the upper digestive tract required to consume and digest food, as well as stimulation of endocrine and exocrine secretions from a wide range of organs. Accordingly, neurons that contribute to feeding behaviors are localized to central, peripheral, and enteric nervous systems. To promote energy balance, feeding circuits must be able to identify and respond to energy requirements, as well as the amount of energy available from internal and external sources, and then direct appropriate coordinated responses throughout the body.

Original languageEnglish (US)
Pages (from-to)1-21
Number of pages21
JournalAnnual Review of Nutrition
Volume33
DOIs
StatePublished - Jul 2013

Fingerprint

Feeding Behavior
Enteric Nervous System
Peripheral Nervous System
Energy Intake
Smooth Muscle
Gastrointestinal Tract
Skeletal Muscle
Homeostasis
Central Nervous System
Head
Neurons
Food

Keywords

  • CNS circuits
  • Energy balance
  • Food intake
  • Obesity

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Functional organization of neuronal and humoral signals regulating feeding behavior. / Schwartz, Gary J.; Zeltser, Lori M.

In: Annual Review of Nutrition, Vol. 33, 07.2013, p. 1-21.

Research output: Contribution to journalArticle

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