Functional activation during an auditory comprehension task in patients with temporal lobe lesions

D. C. Alsop, J. A. Detre, M. D'Esposito, R. S. Howard, J. A. Maldjian, M. Grossman, J. Listerud, Eugene S. Flamm, K. D. Judy, S. W. Atlas

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Functional magnetic resonance imaging (fMRI) was used to map regional brain activation during an auditory comprehension task in two normal controls and two patients with left temporal lobe lesions. Activity in the superior temporal and angular gyrus regions was detected in all normal subjects. In the patients, the spatial distribution of activation ipsilateral to the lesions differed from the pattern observed in contralateral cortex or in control subjects. These studies highlight the potential of fMRI for mapping abnormal functional anatomy in the human brain.

Original languageEnglish (US)
Pages (from-to)55-59
Number of pages5
JournalNeuroImage
Volume4
Issue number1
DOIs
StatePublished - Aug 1996
Externally publishedYes

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Temporal Lobe
Magnetic Resonance Imaging
Parietal Lobe
Brain
Anatomy

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology

Cite this

Alsop, D. C., Detre, J. A., D'Esposito, M., Howard, R. S., Maldjian, J. A., Grossman, M., ... Atlas, S. W. (1996). Functional activation during an auditory comprehension task in patients with temporal lobe lesions. NeuroImage, 4(1), 55-59. https://doi.org/10.1006/nimg.1996.0028

Functional activation during an auditory comprehension task in patients with temporal lobe lesions. / Alsop, D. C.; Detre, J. A.; D'Esposito, M.; Howard, R. S.; Maldjian, J. A.; Grossman, M.; Listerud, J.; Flamm, Eugene S.; Judy, K. D.; Atlas, S. W.

In: NeuroImage, Vol. 4, No. 1, 08.1996, p. 55-59.

Research output: Contribution to journalArticle

Alsop, DC, Detre, JA, D'Esposito, M, Howard, RS, Maldjian, JA, Grossman, M, Listerud, J, Flamm, ES, Judy, KD & Atlas, SW 1996, 'Functional activation during an auditory comprehension task in patients with temporal lobe lesions', NeuroImage, vol. 4, no. 1, pp. 55-59. https://doi.org/10.1006/nimg.1996.0028
Alsop DC, Detre JA, D'Esposito M, Howard RS, Maldjian JA, Grossman M et al. Functional activation during an auditory comprehension task in patients with temporal lobe lesions. NeuroImage. 1996 Aug;4(1):55-59. https://doi.org/10.1006/nimg.1996.0028
Alsop, D. C. ; Detre, J. A. ; D'Esposito, M. ; Howard, R. S. ; Maldjian, J. A. ; Grossman, M. ; Listerud, J. ; Flamm, Eugene S. ; Judy, K. D. ; Atlas, S. W. / Functional activation during an auditory comprehension task in patients with temporal lobe lesions. In: NeuroImage. 1996 ; Vol. 4, No. 1. pp. 55-59.
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