Abstract
Fractionated external beam radiotherapy (EBRT) has multiple roles in the management of intracranial meningiomas. In multiple series post-operative EBRT has shown improved progression-free survival following subtotal resection and a reduction in long-term failures following an apparent gross total resection. In the definitive setting, the use of EBRT has increased as the growing utilization of neuro-imaging for various conditions identifies skull-based lesions which are not easily resectable. Optic nerve sheath meningiomas represent a classic example of the use of definitive EBRT, given the frequent visual sequelae of surgery or observation. EBRT planning is highly individualized and requires a detailed understanding of tumor grade, adjacent radiosensitive structures such as the anterior optic apparatus, and radiographic characteristics of the tumor such as hyperostosis.
Original language | English (US) |
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Pages (from-to) | 349-356 |
Number of pages | 8 |
Journal | Journal of Neuro-Oncology |
Volume | 99 |
Issue number | 3 |
DOIs | |
State | Published - Sep 2010 |
Externally published | Yes |
Keywords
- EBRT
- Fractionated stereotactic radiotherapy
- IMRT
- Meningiomas
- Radiotherapy
ASJC Scopus subject areas
- Oncology
- Neurology
- Clinical Neurology
- Cancer Research