Abstract
We performed a second examination for human papillomavirus (HPV) DNA on 51 sexually experienced 13- to 21-year-old (mean=17.8 years) female patients seen at an urban teaching hospital. Cervicovaginal lavages were performed 6 to 36 months apart (median=13.3 months) to collect cells for HPV DNA detection and typing by Southern blot hybridization. At the first and second visits, 39.2% (20/51) and 25.5% (13/51) of patients, respectively, were infected with HPV. Collectively, 56.9% (29/51) of patients had at least one positive HPV test result. Although 7.8% (4/51) were infected with HPV at both visits, only one patient had infection with the same HPV type. These findings suggest that although HPV infection is a common sexually transmitted disease, genotype-specific HPV infection detected by Southern blot at two visits was rare.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 307-311 |
| Number of pages | 5 |
| Journal | The Journal of Pediatrics |
| Volume | 121 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1992 |
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ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
Cite this
Follow-up evaluation of cervicovaginal human papillomavirus infection in adolescents. / Rosenfeld, Walter D.; Rose, Elizabeth; Vermund, Sten H.; Schreiber, Klaus; Burk, Robert D.
In: The Journal of Pediatrics, Vol. 121, No. 2, 1992, p. 307-311.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Follow-up evaluation of cervicovaginal human papillomavirus infection in adolescents
AU - Rosenfeld, Walter D.
AU - Rose, Elizabeth
AU - Vermund, Sten H.
AU - Schreiber, Klaus
AU - Burk, Robert D.
PY - 1992
Y1 - 1992
N2 - We performed a second examination for human papillomavirus (HPV) DNA on 51 sexually experienced 13- to 21-year-old (mean=17.8 years) female patients seen at an urban teaching hospital. Cervicovaginal lavages were performed 6 to 36 months apart (median=13.3 months) to collect cells for HPV DNA detection and typing by Southern blot hybridization. At the first and second visits, 39.2% (20/51) and 25.5% (13/51) of patients, respectively, were infected with HPV. Collectively, 56.9% (29/51) of patients had at least one positive HPV test result. Although 7.8% (4/51) were infected with HPV at both visits, only one patient had infection with the same HPV type. These findings suggest that although HPV infection is a common sexually transmitted disease, genotype-specific HPV infection detected by Southern blot at two visits was rare.
AB - We performed a second examination for human papillomavirus (HPV) DNA on 51 sexually experienced 13- to 21-year-old (mean=17.8 years) female patients seen at an urban teaching hospital. Cervicovaginal lavages were performed 6 to 36 months apart (median=13.3 months) to collect cells for HPV DNA detection and typing by Southern blot hybridization. At the first and second visits, 39.2% (20/51) and 25.5% (13/51) of patients, respectively, were infected with HPV. Collectively, 56.9% (29/51) of patients had at least one positive HPV test result. Although 7.8% (4/51) were infected with HPV at both visits, only one patient had infection with the same HPV type. These findings suggest that although HPV infection is a common sexually transmitted disease, genotype-specific HPV infection detected by Southern blot at two visits was rare.
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UR - http://www.scopus.com/inward/citedby.url?scp=0026668228&partnerID=8YFLogxK
U2 - 10.1016/S0022-3476(05)81212-0
DO - 10.1016/S0022-3476(05)81212-0
M3 - Article
VL - 121
SP - 307
EP - 311
JO - Journal of Pediatrics
JF - Journal of Pediatrics
SN - 0022-3476
IS - 2
ER -