Abstract
Green fluorescent protein (GFP) from jellyfish Aequorea victoria is the most extensively studied and widely used in cell biology protein. At present novel naturally occurring GFP-like proteins have been discovered and enhanced mutants of Aequorea GFP have been created. These mutants differ from wild-type GFP by stability, value of quantum yield, absorption and fluorescence spectra position and photochemical properties. GFP-like proteins are the fast growing family. This review is an attempt to characterize the main groups of GFP-like proteins, describe their structure and mechanisms of chromophore formation and summarize the main trends of their utilization as markers and biosensors in cell and molecular biology.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 395-420 |
| Number of pages | 26 |
| Journal | Tsitologiya |
| Volume | 49 |
| Issue number | 5 |
| State | Published - 2007 |
Keywords
- Chromoproteins
- Fluorescent proteins
- Photoactivated proteins
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology