TY - JOUR
T1 - Flow index evaluation of 3-d volume flow images
T2 - An in vivo and in vitro study
AU - Dubiel, Mariusz
AU - Hammid, Anissa
AU - Breborowicz, Andrzej
AU - Pietryga, Marek
AU - Sladkevicius, Povilas
AU - Olofsson, Per Åke
AU - Breborowicz, Grzegorz H.
AU - Gudmundsson, Saemundur
N1 - Funding Information:
The Medical Faculty, University of Lund, and the Swedish Society of Medicine supported this study, as well as Malmö University Hospital research funds, the General Maternity Hospital Foundation and a grant from the University School of Medical Sciences, Poznan, Poland, and the University of Poznan, Poland.
PY - 2006/5
Y1 - 2006/5
N2 - Three-dimensional (3-D) ultrasound imaging has improved evaluation of organ circulation and might contribute new information on maternal and fetal blood supply. Flow index (FI) of 3-D color images has been proposed as a measure of perfusion. The aim of this study was to evaluate whether the 3-D FI is a parameter of volume flow and flow velocity in a human vessel and in a flow phantom. A 1-cm-long strip of the uterine artery was recorded in 3-D power Doppler (3D-PD) mode in a cross-sectional study of 170 normal singleton pregnancies between 26 and 42 weeks' gestation. A fixed ultrasound system installation was used during the examination. The VOCAL™ software integrated in the ultrasound unit calculated vessel volume and FI. Reproducibility of the measurements was tested. The method was also tested on a commercially available flow phantom. Reproducibility measurements gave satisfactory results, both in terms of inter- and intraobserver variation. Unexpectedly, in normal pregnancy, the uterine artery FI decreased slightly with gestation. Uterine artery vessel volume increased, however, with gestational age. A poor correlation was found between the FI and both flow velocity and volume flow in the flow phantom. In conclusion, 3D-PD imaging can give impressive anatomical pictures of organ vascular tree. However, the new FI is poorly related to flow velocity or volume of flow. (E-mail: saemundur.gudmundsson@med.lu.se).
AB - Three-dimensional (3-D) ultrasound imaging has improved evaluation of organ circulation and might contribute new information on maternal and fetal blood supply. Flow index (FI) of 3-D color images has been proposed as a measure of perfusion. The aim of this study was to evaluate whether the 3-D FI is a parameter of volume flow and flow velocity in a human vessel and in a flow phantom. A 1-cm-long strip of the uterine artery was recorded in 3-D power Doppler (3D-PD) mode in a cross-sectional study of 170 normal singleton pregnancies between 26 and 42 weeks' gestation. A fixed ultrasound system installation was used during the examination. The VOCAL™ software integrated in the ultrasound unit calculated vessel volume and FI. Reproducibility of the measurements was tested. The method was also tested on a commercially available flow phantom. Reproducibility measurements gave satisfactory results, both in terms of inter- and intraobserver variation. Unexpectedly, in normal pregnancy, the uterine artery FI decreased slightly with gestation. Uterine artery vessel volume increased, however, with gestational age. A poor correlation was found between the FI and both flow velocity and volume flow in the flow phantom. In conclusion, 3D-PD imaging can give impressive anatomical pictures of organ vascular tree. However, the new FI is poorly related to flow velocity or volume of flow. (E-mail: saemundur.gudmundsson@med.lu.se).
KW - 3-D ultrasound
KW - Blood flow
KW - Doppler
KW - Fetus
KW - Flow index
KW - Power Doppler
KW - Pregnancy
KW - Uterine artery
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U2 - 10.1016/j.ultrasmedbio.2006.01.016
DO - 10.1016/j.ultrasmedbio.2006.01.016
M3 - Article
C2 - 16677926
AN - SCOPUS:33646134103
SN - 0301-5629
VL - 32
SP - 665
EP - 671
JO - Ultrasound in Medicine and Biology
JF - Ultrasound in Medicine and Biology
IS - 5
ER -