Fishing for the hidden peptidome in health and disease (Drug Abuse)

Lloyd D. Fricker, Jonathan V. Sweedler

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The proteome and peptidome are defined as the set of proteins and peptides present in a tissue or other biological sample. In most proteomic studies, only abundant proteins are detected and, although these are important molecules, they are often well-studied structural proteins. A number of approaches have been used to examine less abundant molecules that play roles in signaling or otherwise have regulatory functions, including peptides as well as proteins such as enzymes and receptors. The overarching goals of this special issue involve defining the peptidome, identifying the current state of the field, and discussing methods to characterize the peptides, their receptors, and future needs for such measurements.

Original languageEnglish (US)
Pages (from-to)679-682
Number of pages4
JournalAAPS Journal
Volume12
Issue number4
DOIs
StatePublished - Dec 2010

Fingerprint

Substance-Related Disorders
Health
Proteins
Peptides
Peptide Receptors
Proteome
Proteomics
Enzymes

Keywords

  • Biomarker
  • Peptidase
  • Peptides
  • Peptidomics
  • Proteomics

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Fishing for the hidden peptidome in health and disease (Drug Abuse). / Fricker, Lloyd D.; Sweedler, Jonathan V.

In: AAPS Journal, Vol. 12, No. 4, 12.2010, p. 679-682.

Research output: Contribution to journalArticle

Fricker, Lloyd D. ; Sweedler, Jonathan V. / Fishing for the hidden peptidome in health and disease (Drug Abuse). In: AAPS Journal. 2010 ; Vol. 12, No. 4. pp. 679-682.
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