First-trimester diagnosis of familial split-hand/split-foot malformation

Kavitha T. Ram, Dena Goffman, John Ilagan, Pe'er Dar

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Split-hand/split-foot malformation (SHFM), also called lobster claw deformity or ectrodactyly, is a rare congenital defect expressed as a median cleft of hands, feet, or both due to the absence of the central rays. The reported incidence is approximately 1 per 90,000. The anomaly results from abnormal development of the hand and foot plates during the seventh week of gestation. The malformations can be isolated to the hands and feet with variable expression or more commonly may be seen as part of a syndrome. Typical and atypical forms are recognized. The typical variety has a V-shaped central defect, whereas the atypical form, usually sporadic, has a U-shaped cleft. Advancements in screening sonography have led to the potential for detecting this rare malformation at mid gestation. We report a case of familial SHFM diagnosed by transvaginal sonography at 11 weeks' gestation.

Original languageEnglish (US)
Pages (from-to)1397-1400
Number of pages4
JournalJournal of Ultrasound in Medicine
Volume28
Issue number10
StatePublished - Oct 1 2009

Fingerprint

First Pregnancy Trimester
Foot
Hand
Pregnancy
Ultrasonography
Hoof and Claw
Incidence

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Medicine(all)

Cite this

First-trimester diagnosis of familial split-hand/split-foot malformation. / Ram, Kavitha T.; Goffman, Dena; Ilagan, John; Dar, Pe'er.

In: Journal of Ultrasound in Medicine, Vol. 28, No. 10, 01.10.2009, p. 1397-1400.

Research output: Contribution to journalArticle

Ram, Kavitha T. ; Goffman, Dena ; Ilagan, John ; Dar, Pe'er. / First-trimester diagnosis of familial split-hand/split-foot malformation. In: Journal of Ultrasound in Medicine. 2009 ; Vol. 28, No. 10. pp. 1397-1400.
@article{b6aa3b797caf4b52889025a867082d8d,
title = "First-trimester diagnosis of familial split-hand/split-foot malformation",
abstract = "Split-hand/split-foot malformation (SHFM), also called lobster claw deformity or ectrodactyly, is a rare congenital defect expressed as a median cleft of hands, feet, or both due to the absence of the central rays. The reported incidence is approximately 1 per 90,000. The anomaly results from abnormal development of the hand and foot plates during the seventh week of gestation. The malformations can be isolated to the hands and feet with variable expression or more commonly may be seen as part of a syndrome. Typical and atypical forms are recognized. The typical variety has a V-shaped central defect, whereas the atypical form, usually sporadic, has a U-shaped cleft. Advancements in screening sonography have led to the potential for detecting this rare malformation at mid gestation. We report a case of familial SHFM diagnosed by transvaginal sonography at 11 weeks' gestation.",
author = "Ram, {Kavitha T.} and Dena Goffman and John Ilagan and Pe'er Dar",
year = "2009",
month = "10",
day = "1",
language = "English (US)",
volume = "28",
pages = "1397--1400",
journal = "Journal of Ultrasound in Medicine",
issn = "0278-4297",
publisher = "American Institute of Ultrasound in Medicine",
number = "10",

}

TY - JOUR

T1 - First-trimester diagnosis of familial split-hand/split-foot malformation

AU - Ram, Kavitha T.

AU - Goffman, Dena

AU - Ilagan, John

AU - Dar, Pe'er

PY - 2009/10/1

Y1 - 2009/10/1

N2 - Split-hand/split-foot malformation (SHFM), also called lobster claw deformity or ectrodactyly, is a rare congenital defect expressed as a median cleft of hands, feet, or both due to the absence of the central rays. The reported incidence is approximately 1 per 90,000. The anomaly results from abnormal development of the hand and foot plates during the seventh week of gestation. The malformations can be isolated to the hands and feet with variable expression or more commonly may be seen as part of a syndrome. Typical and atypical forms are recognized. The typical variety has a V-shaped central defect, whereas the atypical form, usually sporadic, has a U-shaped cleft. Advancements in screening sonography have led to the potential for detecting this rare malformation at mid gestation. We report a case of familial SHFM diagnosed by transvaginal sonography at 11 weeks' gestation.

AB - Split-hand/split-foot malformation (SHFM), also called lobster claw deformity or ectrodactyly, is a rare congenital defect expressed as a median cleft of hands, feet, or both due to the absence of the central rays. The reported incidence is approximately 1 per 90,000. The anomaly results from abnormal development of the hand and foot plates during the seventh week of gestation. The malformations can be isolated to the hands and feet with variable expression or more commonly may be seen as part of a syndrome. Typical and atypical forms are recognized. The typical variety has a V-shaped central defect, whereas the atypical form, usually sporadic, has a U-shaped cleft. Advancements in screening sonography have led to the potential for detecting this rare malformation at mid gestation. We report a case of familial SHFM diagnosed by transvaginal sonography at 11 weeks' gestation.

UR - http://www.scopus.com/inward/record.url?scp=74749105596&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=74749105596&partnerID=8YFLogxK

M3 - Article

C2 - 19778890

AN - SCOPUS:74749105596

VL - 28

SP - 1397

EP - 1400

JO - Journal of Ultrasound in Medicine

JF - Journal of Ultrasound in Medicine

SN - 0278-4297

IS - 10

ER -