First-generation linkage map of the warningly colored butterfly Heliconius erato

A. Tobler, D. Kapan, N. S. Flanagan, C. Gonzalez, E. Peterson, C. D. Jiggins, J. S. Johntson, D. G. Heckel, W. O. McMillan

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

We report the first genetic linkage map of Heliconius erato, a species that shows remarkable variation in its warningly colored wing patterns. We use crosses between H. erato and its sister species, H. himera, to place two major color pattern genes, D and Cr, on a linkage map containing AFLP, allozyme, microsatellite and single-copy nuclear loci. We identified all 21 linkage groups in an initial genetic screen of 22 progeny from an F1 female x male H. himera family. Of the 229 markers, 87 used to identify linkage groups were also informative in 35 progeny from a sibling backcross (H. himera female x F1 male). With these, and an additional 33 markers informative in the second family, we constructed recombinational maps for 19 of the 21 linkage groups. These maps varied in length from 18.1 to 431.1 centimorgans (cM) and yielded an estimated total length of 2400 cM. The average distance between markers was 23 cM, and eight of the 19 linkage groups, including the sex chromosome (Z) and the chromosome containing the Cr locus, contained two or more codominant anchor loci. Of the three potential candidate genes mapped here, Cubitus interruptus (Ci), Decapentaplegic (Dpp) and Wingless (Wg), only Ci was linked, although loosely, to a known Heliconius color pattern locus. This work is an important first step for constructing a denser genetic map of the H. erato color pattern radiation and for a comparative genomic study of the architecture of mimicry in Heliconius butterflies.

Original languageEnglish (US)
Pages (from-to)408-417
Number of pages10
JournalHeredity
Volume94
Issue number4
DOIs
StatePublished - Apr 2005
Externally publishedYes

Fingerprint

Butterflies
linkage groups
butterflies
chromosome mapping
Color
Heliconius
loci
color
Sex Chromosomes
Genetic Linkage
Microsatellite Repeats
Isoenzymes
Genes
sex chromosomes
Chromosomes
allozymes
Radiation
amplified fragment length polymorphism
genes
microsatellite repeats

Keywords

  • Adaptation
  • AFLP
  • Color pattern
  • Microsatellites
  • Mimicry
  • Single-copy nuclear loci

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Genetics
  • Genetics(clinical)

Cite this

Tobler, A., Kapan, D., Flanagan, N. S., Gonzalez, C., Peterson, E., Jiggins, C. D., ... McMillan, W. O. (2005). First-generation linkage map of the warningly colored butterfly Heliconius erato. Heredity, 94(4), 408-417. https://doi.org/10.1038/sj.hdy.6800619

First-generation linkage map of the warningly colored butterfly Heliconius erato. / Tobler, A.; Kapan, D.; Flanagan, N. S.; Gonzalez, C.; Peterson, E.; Jiggins, C. D.; Johntson, J. S.; Heckel, D. G.; McMillan, W. O.

In: Heredity, Vol. 94, No. 4, 04.2005, p. 408-417.

Research output: Contribution to journalArticle

Tobler, A, Kapan, D, Flanagan, NS, Gonzalez, C, Peterson, E, Jiggins, CD, Johntson, JS, Heckel, DG & McMillan, WO 2005, 'First-generation linkage map of the warningly colored butterfly Heliconius erato', Heredity, vol. 94, no. 4, pp. 408-417. https://doi.org/10.1038/sj.hdy.6800619
Tobler A, Kapan D, Flanagan NS, Gonzalez C, Peterson E, Jiggins CD et al. First-generation linkage map of the warningly colored butterfly Heliconius erato. Heredity. 2005 Apr;94(4):408-417. https://doi.org/10.1038/sj.hdy.6800619
Tobler, A. ; Kapan, D. ; Flanagan, N. S. ; Gonzalez, C. ; Peterson, E. ; Jiggins, C. D. ; Johntson, J. S. ; Heckel, D. G. ; McMillan, W. O. / First-generation linkage map of the warningly colored butterfly Heliconius erato. In: Heredity. 2005 ; Vol. 94, No. 4. pp. 408-417.
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