Feasibility of a physical activity intervention for obese, socioculturally diverse endometrial cancer survivors

Amerigo Rossi, Carol Ewing Garber, Monica Ortiz, Shankar Viswanathan, Gary L. Goldberg, Nicole S. Nevadunsky

Research output: Contribution to journalArticle

12 Scopus citations


Purpose Determine the feasibility of a 12-week physical activity intervention for obese, socioculturally diverse endometrial cancer survivors and to evaluate whether the intervention improves physical activity behavior, physical function, waist circumference, and quality of life. Methods Obese endometrial cancer survivors from Bronx, NY were assigned to either a 12-week physical activity intervention of behavioral counseling, physical activity and home-based walking (n = 25), or wait-list control group (n = 15). Mixed-design ANOVA (2 groups × 2 time points) were analyzed to determine differences between the intervention and the control for the Yale Physical Activity Survey, six-minute walk test, 30-second chair stand test, waist circumference, and Functional Assessment of Cancer Therapy-Endometrial questionnaire. Data are presented as mean ± standard deviation. Results The sample was diverse (38% non-Hispanic black, 38% Hispanic, 19% non-Hispanic white). Mean Body Mass Index was 37.3 ± 6.5 kg·m− 2. Although recruitment rate was low (20% of 140 contacted), 15 of 25 participants in the intervention group attended 75–100% of scheduled sessions. Participants reported walking 118 ± 79 min/week at home. There were large effect sizes for the improvements in the six-minute walk test (22 ± 17 m vs. 1 ± 22 m, d = 1.10), waist circumference (− 5.3 ± 5.3 cm vs. 2.6 ± 6.7 cm, d = − 1.32), quality of life (10 ± 12 vs. − 1 ± 11, d = 0.86) and walking self-efficacy (24 ± 30% vs. 1 ± 55%, d = 0.87) compared to the control group. Conclusions The intervention appeared feasible in this population. The results show promising effects on several outcomes that should be confirmed in a larger randomized control trial, with more robust recruitment strategies.

Original languageEnglish (US)
Pages (from-to)304-310
Number of pages7
JournalGynecologic Oncology
Issue number2
StatePublished - Aug 1 2016



  • Endometrial cancer
  • Ethnicity
  • Obesity
  • Physical activity
  • Quality of life

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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