Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation

Richard P. Chalwin, Ravindranath Tiruvoipati, Giles J. Peek

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown

Original languageEnglish (US)
Pages (from-to)685-686
Number of pages2
JournalEuropean Journal of Cardio-thoracic Surgery
Volume34
Issue number3
DOIs
StatePublished - Sep 2008
Externally publishedYes

Fingerprint

Factor VIIa
Extracorporeal Membrane Oxygenation
Thrombosis
Life Support Systems
Pediatrics
Hemorrhage
Crowns
Pharmaceutical Preparations
recombinant FVIIa

Keywords

  • Bleeding
  • Extracorporeal membrane oxygenation
  • Thrombosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation. / Chalwin, Richard P.; Tiruvoipati, Ravindranath; Peek, Giles J.

In: European Journal of Cardio-thoracic Surgery, Vol. 34, No. 3, 09.2008, p. 685-686.

Research output: Contribution to journalArticle

@article{26e15515708347d988a2e19a9b83b5b2,
title = "Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation",
abstract = "Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown",
keywords = "Bleeding, Extracorporeal membrane oxygenation, Thrombosis",
author = "Chalwin, {Richard P.} and Ravindranath Tiruvoipati and Peek, {Giles J.}",
year = "2008",
month = "9",
doi = "10.1016/j.ejcts.2008.05.022",
language = "English (US)",
volume = "34",
pages = "685--686",
journal = "European Journal of Cardio-thoracic Surgery",
issn = "1010-7940",
publisher = "Elsevier",
number = "3",

}

TY - JOUR

T1 - Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation

AU - Chalwin, Richard P.

AU - Tiruvoipati, Ravindranath

AU - Peek, Giles J.

PY - 2008/9

Y1 - 2008/9

N2 - Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown

AB - Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown

KW - Bleeding

KW - Extracorporeal membrane oxygenation

KW - Thrombosis

UR - http://www.scopus.com/inward/record.url?scp=49149132047&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49149132047&partnerID=8YFLogxK

U2 - 10.1016/j.ejcts.2008.05.022

DO - 10.1016/j.ejcts.2008.05.022

M3 - Article

VL - 34

SP - 685

EP - 686

JO - European Journal of Cardio-thoracic Surgery

JF - European Journal of Cardio-thoracic Surgery

SN - 1010-7940

IS - 3

ER -