Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation

Richard P. Chalwin; Ravindranath Tiruvoipati; Giles J. Peek

doi:10.1016/j.ejcts.2008.05.022

Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation

Richard P. Chalwin, Ravindranath Tiruvoipati, Giles J. Peek

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown

Original language	English (US)
Pages (from-to)	685-686
Number of pages	2
Journal	European Journal of Cardio-thoracic Surgery
Volume	34
Issue number	3
DOIs	https://doi.org/10.1016/j.ejcts.2008.05.022
State	Published - Sep 2008
Externally published	Yes

Keywords

Bleeding
Extracorporeal membrane oxygenation
Thrombosis

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine

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10.1016/j.ejcts.2008.05.022

Cite this

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title = "Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation",

abstract = "Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown",

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AU - Chalwin, Richard P.

AU - Tiruvoipati, Ravindranath

AU - Peek, Giles J.

PY - 2008/9

Y1 - 2008/9

N2 - Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown

AB - Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown

KW - Bleeding

KW - Extracorporeal membrane oxygenation

KW - Thrombosis

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Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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