Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenation

Richard P. Chalwin, Ravindranath Tiruvoipati, Giles J. Peek

Research output: Contribution to journalArticle

25 Scopus citations


Bleeding remains a potential complication for patients requiring extracorporeal life support systems. Recombinant activated factor VII (rFVIIa) is one of the drugs used in controlling bleeding. Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis. Crown

Original languageEnglish (US)
Pages (from-to)685-686
Number of pages2
JournalEuropean Journal of Cardio-thoracic Surgery
Issue number3
Publication statusPublished - Sep 1 2008



  • Bleeding
  • Extracorporeal membrane oxygenation
  • Thrombosis

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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