Familial mediterranean fever

Norman Todd Ilowite, P. Lanzkowsky, S. Schiff, M. Gandhi, I. R. Shenker, B. Gauthier, A. Battista

Research output: Contribution to journalArticle

Abstract

A 7-year-old Lebanese female had had intermittent episodes of abdominal pain, constipation, vomiting, shortness of breath, chest pain and fever up to 40°C lasting two to three days every one to two months since birth. Over the past year the symptoms had increased in frequency, occurring every one to two weeks. There was no Raynaud's phenomenon, oral ulcerations, alopecia and photosensitivity. Physical examination showed a malar blush but was otherwise normal. The differential diagnosis included the FAPA syndrome, cyclic neutropenia, the hyper-IgD syndrome and familial mediterranean fever (FMF). The clinical findings excluded the first three conditions, and left FMF as the probable diagnosis. This was supported by the fact that the patient had a brother and sister with a similar illness. Untreated FMF frequently leads to amyloidosis. The administration of colchicine is effective at controlling the disease and preventing progression to amyloidosis.

Original languageEnglish (US)
Pages (from-to)29-30
Number of pages2
JournalChildren's Hospital Quarterly
Volume8
Issue number1
StatePublished - 1996
Externally publishedYes

Fingerprint

Familial Mediterranean Fever
Amyloidosis
Siblings
Mevalonate Kinase Deficiency
Raynaud Disease
Alopecia
Colchicine
Constipation
Chest Pain
Dyspnea
Abdominal Pain
Physical Examination
Vomiting
Disease Progression
Differential Diagnosis
Fever
Parturition

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Ilowite, N. T., Lanzkowsky, P., Schiff, S., Gandhi, M., Shenker, I. R., Gauthier, B., & Battista, A. (1996). Familial mediterranean fever. Children's Hospital Quarterly, 8(1), 29-30.

Familial mediterranean fever. / Ilowite, Norman Todd; Lanzkowsky, P.; Schiff, S.; Gandhi, M.; Shenker, I. R.; Gauthier, B.; Battista, A.

In: Children's Hospital Quarterly, Vol. 8, No. 1, 1996, p. 29-30.

Research output: Contribution to journalArticle

Ilowite, NT, Lanzkowsky, P, Schiff, S, Gandhi, M, Shenker, IR, Gauthier, B & Battista, A 1996, 'Familial mediterranean fever', Children's Hospital Quarterly, vol. 8, no. 1, pp. 29-30.
Ilowite NT, Lanzkowsky P, Schiff S, Gandhi M, Shenker IR, Gauthier B et al. Familial mediterranean fever. Children's Hospital Quarterly. 1996;8(1):29-30.
Ilowite, Norman Todd ; Lanzkowsky, P. ; Schiff, S. ; Gandhi, M. ; Shenker, I. R. ; Gauthier, B. ; Battista, A. / Familial mediterranean fever. In: Children's Hospital Quarterly. 1996 ; Vol. 8, No. 1. pp. 29-30.
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