Familial congestive cardiomyopathy with nemaline rods in heart and skeletal muscle

Joan G. Jones, Stephen M. Factor

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Primary familial cardiomyopathy, once exclusively associated with hypertrophic disorders, is now recognized to occur in a dilated or congestive form. In some instances, characteristic myocellular inclusions of varying morphologies have been identified. Nemaline rods are inclusions which typically have been linked with a rather benign and nonprogressive congenital myopathy. We report finding myocellular inclusions consistent with nemaline rods in two brother who died with congestive cardiomyopathy. Although there was no history or clinical evidence of a myopathy, characteristic nemaline rod inclusions were also identified in the skeletal muscle of one sibling.

Original languageEnglish (US)
Pages (from-to)307-312
Number of pages6
JournalVirchows Archiv A Pathological Anatomy and Histopathology
Issue number2-3
StatePublished - Mar 1 1985


  • Familial cardiomyopathy
  • Myopathy
  • Nemaline rods

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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