Factors that affect the postnatal increase in superior mesenteric artery blood flow velocity in very low birth weight preterm infants

Thomas Havranek, Branko Miladinovic, Rajan Wadhawan, Jane D. Carver

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Objective: To identify factors related to the postnatal increase in superior mesenteric artery blood flow velocity (SMA BFV). Study design: SMA BFV was measured in 35 infants (birth weight 1047 ± 246 g) on day of life (DOL) 1, 3, 5, 7 10 and 14. Latent curve modeling (LCM) was used to measure the longitudinal change in BFV for each subject, and the correlation between changes in BFV and baseline values. Non-parametric correlations were calculated between BFV and variables previously reported to be related to SMA BFV. Results: There was significant variability in SMA BFV on DOL 1, a significant increase from DOL 1 - 14, and signifi- cant variability in the postnatal increase. Infants with higher enteral feeding volumes had greater increases, while infants receiving positive pressure ventilation or hyperalimentation had lower increases. Conclusions: Several clinical factors affect the postnatal increase in SMA BFV. The use of LCM is useful in longitudinal studies of very low birth weight (VLBW) infants, who are clinically and demographically heterogeneous.

Original languageEnglish (US)
Pages (from-to)565-570
Number of pages6
JournalJournal of Perinatal Medicine
Volume40
Issue number5
DOIs
StatePublished - Sep 1 2012
Externally publishedYes

Keywords

  • Doppler ultrasound
  • Intestinal blood flow
  • Latent curve modeling

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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