Factors contributing to ventriculostomy infection

Joon Hyung Kim, Naman S. Desai, Joseph Ricci, Philip E. Stieg, Axel J. Rosengart, Roger Hrtl, Justin F. Fraser

Research output: Contribution to journalReview articlepeer-review

56 Scopus citations

Abstract

Objective: Catheter-related infection remains a cause of morbidity in the use of external ventricular drains (EVDs). The aim of this retrospective single-center study was to assess the rate and factors related to ventriculostomy infections in the setting of the published literature. Methods: Patients that underwent EVD placement in a single-center were retrospectively reviewed. Diagnosis, treatment, hospital course, and infection-related data were collected and analyzed in reference to ventriculitis rates. The protocols for EVD placement and maintenance were reviewed. Results: Of 343 patients, 12 acquired an EVD infection. No significant differences existed between those with and without ventriculitis for age, sex, underlying diagnosis, or concomitant systemic infection. Although not significant, concomitant systemic infection existed in 4.7% of patients with ventriculitis versus 1.5% without. There was a significant difference in length of EVD placement in patients with ventriculitis (20.9 ± 15.3 days) versus those without (12.1 ± 18.2; P = 0.005). Coagulase-negative Staphylococcus and Staphylococcus aureus represented the most commonly associated pathogens. With an overall cumulative incidence of 3.5%, our rate compared favorably to the published literature (cumulative incidence 9.5%; range, 3.9%-23.2%). Conclusions: Catheter-related infection remains an important complication of EVD placement. Of factors evaluated, length of time of catheter placement has the most notable relationship to infection incidence, suggesting that early drain removal should be a goal whenever medically appropriate.

Original languageEnglish (US)
Pages (from-to)135-140
Number of pages6
JournalWorld Neurosurgery
Volume77
Issue number1
DOIs
StatePublished - Jan 2012
Externally publishedYes

Keywords

  • External ventricular drain
  • Infection
  • Ventriculitis
  • Ventriculostomy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Factors contributing to ventriculostomy infection'. Together they form a unique fingerprint.

Cite this