Factors Associated with Prescription of Opioids and Co-prescription of Sedating Medications in Individuals with HIV

Jessica S. Merlin, Ashutosh Tamhane, Joanna L. Starrels, Stefan Kertesz, Michael Saag, Karen Cropsey

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Opioids are often prescribed for chronic pain, and opioid risks such as overdose and death are heightened when opioids are co-prescribed with other sedating medications. We investigated factors associated with chronic opioid prescription, alone and in combination with benzodiazepines and muscle relaxants, in a clinical cohort of individuals with HIV. We used multivariable logistic regression models to determine participant clinical and demographic characteristics that are associated with chronic prescription of opioids or chronic co-prescription of opioids with sedating medications. Among 1474 participants, chronic prescription of opioids occurred in 253 individuals (17.2 %), and chronic co-prescription occurred in 90 individuals (6.1 %). Age >50, public insurance as compared to private insurance, and symptoms of depression and anxiety were significantly associated with chronic opioid prescription and chronic co-prescription. Our findings raise concern that opioid prescription and co-prescription of sedating medications occurs disproportionately in patients for whom use is riskier.

Original languageEnglish (US)
Pages (from-to)687-698
Number of pages12
JournalAIDS and Behavior
Volume20
Issue number3
DOIs
StatePublished - Mar 1 2016

Keywords

  • Benzodiazepine
  • Chronic pain
  • HIV
  • Muscle relaxant
  • Opioid

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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