TY - JOUR
T1 - Facilitators and barriers to successful recruitment into a large comparative effectiveness trial
T2 - a qualitative study
AU - GRADE Research Group
AU - Behringer-Massera, Stephanie
AU - Browne, Terysia
AU - George, Geny
AU - Duran, Sally
AU - Cherrington, Andrea
AU - McKee, M. Diane
N1 - Copyright:
This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine
PY - 2019/7/1
Y1 - 2019/7/1
N2 - Background: Recruitment of participants into research studies, especially individuals from minority groups, is challenging; lack of diversity may lead to biased findings. Aim: To explore beliefs about research participation among individuals who were approached and eligible for the GRADE study. Methods: In-depth qualitative telephone interviews with randomized participants (n = 25) and eligible individuals who declined to enroll (n = 26). Results: Refusers and consenters differed in trust and perceptions of risk, benefits and burden of participation. Few participants understood how comparative effectiveness research differed from other types of trials; however, some features of comparative effectiveness research were perceived as lower risk. Conclusion: We identified facilitators and addressable barriers to participation in research studies.
AB - Background: Recruitment of participants into research studies, especially individuals from minority groups, is challenging; lack of diversity may lead to biased findings. Aim: To explore beliefs about research participation among individuals who were approached and eligible for the GRADE study. Methods: In-depth qualitative telephone interviews with randomized participants (n = 25) and eligible individuals who declined to enroll (n = 26). Results: Refusers and consenters differed in trust and perceptions of risk, benefits and burden of participation. Few participants understood how comparative effectiveness research differed from other types of trials; however, some features of comparative effectiveness research were perceived as lower risk. Conclusion: We identified facilitators and addressable barriers to participation in research studies.
KW - comparative effectiveness research
KW - qualitative research
KW - recruitment
UR - http://www.scopus.com/inward/record.url?scp=85071702144&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85071702144&partnerID=8YFLogxK
U2 - 10.2217/cer-2019-0010
DO - 10.2217/cer-2019-0010
M3 - Article
C2 - 31368793
AN - SCOPUS:85071702144
VL - 8
SP - 815
EP - 826
JO - Journal of Comparative Effectiveness Research
JF - Journal of Comparative Effectiveness Research
SN - 2042-6305
IS - 10
ER -