Facile formation of dehydroalanine from S-nitrosocysteines

Hua Wang, Jiming Zhang, Ming Xian

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

(Chemical Equation Presented) A reductive elimination of S-nitrosocysteines using phosphine substrates has been developed. This reaction converts unstable S-nitrosocysteines to dehydroalanine derivatives under very mild conditions. It can potentially be applied for the detection of protein S-nitrosation.

Original languageEnglish (US)
Pages (from-to)13238-13239
Number of pages2
JournalJournal of the American Chemical Society
Volume131
Issue number37
DOIs
StatePublished - Sep 23 2009
Externally publishedYes

Fingerprint

phosphine
Nitrosation
Derivatives
Proteins
Protein S
Substrates
dehydroalanine
S-nitrosocysteine

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Facile formation of dehydroalanine from S-nitrosocysteines. / Wang, Hua; Zhang, Jiming; Xian, Ming.

In: Journal of the American Chemical Society, Vol. 131, No. 37, 23.09.2009, p. 13238-13239.

Research output: Contribution to journalArticle

Wang, Hua ; Zhang, Jiming ; Xian, Ming. / Facile formation of dehydroalanine from S-nitrosocysteines. In: Journal of the American Chemical Society. 2009 ; Vol. 131, No. 37. pp. 13238-13239.
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