Facile formation of dehydroalanine from S-nitrosocysteines

Hua Wang; Jiming Zhang; Ming Xian

doi:10.1021/ja905558w

Facile formation of dehydroalanine from S-nitrosocysteines

Hua Wang, Jiming Zhang, Ming Xian

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

(Chemical Equation Presented) A reductive elimination of S-nitrosocysteines using phosphine substrates has been developed. This reaction converts unstable S-nitrosocysteines to dehydroalanine derivatives under very mild conditions. It can potentially be applied for the detection of protein S-nitrosation.

Original language	English (US)
Pages (from-to)	13238-13239
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	131
Issue number	37
DOIs	https://doi.org/10.1021/ja905558w
State	Published - Sep 23 2009
Externally published	Yes

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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title = "Facile formation of dehydroalanine from S-nitrosocysteines",

abstract = "(Chemical Equation Presented) A reductive elimination of S-nitrosocysteines using phosphine substrates has been developed. This reaction converts unstable S-nitrosocysteines to dehydroalanine derivatives under very mild conditions. It can potentially be applied for the detection of protein S-nitrosation.",

author = "Hua Wang and Jiming Zhang and Ming Xian",

year = "2009",

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doi = "10.1021/ja905558w",

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AU - Wang, Hua

AU - Zhang, Jiming

AU - Xian, Ming

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N2 - (Chemical Equation Presented) A reductive elimination of S-nitrosocysteines using phosphine substrates has been developed. This reaction converts unstable S-nitrosocysteines to dehydroalanine derivatives under very mild conditions. It can potentially be applied for the detection of protein S-nitrosation.

AB - (Chemical Equation Presented) A reductive elimination of S-nitrosocysteines using phosphine substrates has been developed. This reaction converts unstable S-nitrosocysteines to dehydroalanine derivatives under very mild conditions. It can potentially be applied for the detection of protein S-nitrosation.

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JO - Journal of the American Chemical Society

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Facile formation of dehydroalanine from S-nitrosocysteines

Abstract

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