This study provides longitudinal data showing that treatment with haloperidol produced no change in smooth pursuit eye movement compared to performance during unmedicated trials. Normal pursuit remained intact and abnormal pursuit remained deviant despite a significant reduction in the severity of psychotic symptoms. Three of four patients in both the standard and high dose groups showed normal pursuit throughout the first month of drug treatment. Thus it seems unlikely that impaired SPEM in medicated psychotic patients can be explained as an acute effect of antipsychotic drugs.
|Original language||English (US)|
|Number of pages||7|
|State||Published - 1983|
ASJC Scopus subject areas
- Biological Psychiatry