Eye tracking dysfunction unrelated to clinical state and treatment with haloperidol

D. L. Levy, R. B. Lipton, P. S. Holzman, J. M. Davis

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

This study provides longitudinal data showing that treatment with haloperidol produced no change in smooth pursuit eye movement compared to performance during unmedicated trials. Normal pursuit remained intact and abnormal pursuit remained deviant despite a significant reduction in the severity of psychotic symptoms. Three of four patients in both the standard and high dose groups showed normal pursuit throughout the first month of drug treatment. Thus it seems unlikely that impaired SPEM in medicated psychotic patients can be explained as an acute effect of antipsychotic drugs.

Original languageEnglish (US)
Pages (from-to)813-819
Number of pages7
JournalBiological Psychiatry
Volume18
Issue number7
StatePublished - Dec 1 1983
Externally publishedYes

ASJC Scopus subject areas

  • Biological Psychiatry

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