Extranodal non-T-cell lymphoblastic lymphoma in adults. A report of two cases

V. S. Schwob, L. Weiner, G. Hudes, H. Ratech

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Typical adult cases of malignant lymphoma, diffuse, lymphoblastic type (MLLB), are of the T-cell immunophenotype and occur as mediastinal masses. The authors report two unusual adult cases with initial extranodal sites of involvement and non-T-cell immunophenotype that were originally misclassified. One patient presented with a right submaxillary salivary gland mass and the other presented with a T7-8 spinal cord compression resulting from a vertebral body tumor. A lymphoblastic leukemic phase developed in both patients after 15 months and 5 months, respectively. The bone marrow blasts of both patients had positive results for cluster designation (CD) 10, CD19, HLA-DR, and terminal deoxynucleotidyl transferase. Because both extranodal sites of presentation and non-T-cell immunophenotype are unusual in adult MLLB, these features may have contributed to the original misclassification of these lesions.

Original languageEnglish (US)
Pages (from-to)602-605
Number of pages4
JournalAmerican Journal of Clinical Pathology
Volume90
Issue number5
StatePublished - 1988
Externally publishedYes

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Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lymphoma
Spinal Cord Compression
DNA Nucleotidylexotransferase
Submandibular Gland
HLA-DR Antigens
Salivary Glands
Bone Marrow
T-Lymphocytes
Neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Schwob, V. S., Weiner, L., Hudes, G., & Ratech, H. (1988). Extranodal non-T-cell lymphoblastic lymphoma in adults. A report of two cases. American Journal of Clinical Pathology, 90(5), 602-605.

Extranodal non-T-cell lymphoblastic lymphoma in adults. A report of two cases. / Schwob, V. S.; Weiner, L.; Hudes, G.; Ratech, H.

In: American Journal of Clinical Pathology, Vol. 90, No. 5, 1988, p. 602-605.

Research output: Contribution to journalArticle

Schwob, VS, Weiner, L, Hudes, G & Ratech, H 1988, 'Extranodal non-T-cell lymphoblastic lymphoma in adults. A report of two cases', American Journal of Clinical Pathology, vol. 90, no. 5, pp. 602-605.
Schwob, V. S. ; Weiner, L. ; Hudes, G. ; Ratech, H. / Extranodal non-T-cell lymphoblastic lymphoma in adults. A report of two cases. In: American Journal of Clinical Pathology. 1988 ; Vol. 90, No. 5. pp. 602-605.
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