Extrahepatic Complications of Nonalcoholic Fatty Liver Disease

Kristina R. Chacko; John Reinus

doi:10.1016/j.cld.2015.10.004

Extrahepatic Complications of Nonalcoholic Fatty Liver Disease

Kristina R. Chacko, John Reinus

Medicine

Research output: Contribution to journal › Review article › peer-review

51 Scopus citations

Abstract

Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver disease that is often associated with the metabolic syndrome. There is a growing awareness that extrahepatic complications occur in individuals with NAFLD, especially an increased risk of cardiovascular disease. Development of diabetes mellitus, chronic kidney disease, colorectal cancer, and endocrinopathies has been linked to NAFLD. This article reviews the extrahepatic complications affecting individuals with NAFLD and the pathogenesis underlying their development.

Original language	English (US)
Pages (from-to)	387-401
Number of pages	15
Journal	Clinics in Liver Disease
Volume	20
Issue number	2
DOIs	https://doi.org/10.1016/j.cld.2015.10.004
State	Published - May 1 2016

Keywords

Cardiovascular disease
Extrahepatic complications
Metabolic syndrome
Nonalcoholic fatty liver disease (NAFLD)

ASJC Scopus subject areas

Hepatology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.cld.2015.10.004

Cite this

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title = "Extrahepatic Complications of Nonalcoholic Fatty Liver Disease",

abstract = "Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver disease that is often associated with the metabolic syndrome. There is a growing awareness that extrahepatic complications occur in individuals with NAFLD, especially an increased risk of cardiovascular disease. Development of diabetes mellitus, chronic kidney disease, colorectal cancer, and endocrinopathies has been linked to NAFLD. This article reviews the extrahepatic complications affecting individuals with NAFLD and the pathogenesis underlying their development.",

keywords = "Cardiovascular disease, Extrahepatic complications, Metabolic syndrome, Nonalcoholic fatty liver disease (NAFLD)",

author = "Chacko, {Kristina R.} and John Reinus",

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T1 - Extrahepatic Complications of Nonalcoholic Fatty Liver Disease

AU - Chacko, Kristina R.

AU - Reinus, John

PY - 2016/5/1

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N2 - Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver disease that is often associated with the metabolic syndrome. There is a growing awareness that extrahepatic complications occur in individuals with NAFLD, especially an increased risk of cardiovascular disease. Development of diabetes mellitus, chronic kidney disease, colorectal cancer, and endocrinopathies has been linked to NAFLD. This article reviews the extrahepatic complications affecting individuals with NAFLD and the pathogenesis underlying their development.

AB - Nonalcoholic fatty liver disease (NAFLD) is an important cause of liver disease that is often associated with the metabolic syndrome. There is a growing awareness that extrahepatic complications occur in individuals with NAFLD, especially an increased risk of cardiovascular disease. Development of diabetes mellitus, chronic kidney disease, colorectal cancer, and endocrinopathies has been linked to NAFLD. This article reviews the extrahepatic complications affecting individuals with NAFLD and the pathogenesis underlying their development.

KW - Cardiovascular disease

KW - Extrahepatic complications

KW - Metabolic syndrome

KW - Nonalcoholic fatty liver disease (NAFLD)

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SN - 1089-3261

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JO - Clinics in Liver Disease

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IS - 2

ER -

Extrahepatic Complications of Nonalcoholic Fatty Liver Disease

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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